Results 91 to 100 of about 859,407 (298)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
A Note on the Total Detection Numbers of Cycles
Discussiones Mathematicae Graph Theory, 2015 Let G be a connected graph of size at least 2 and c :E(G)→{0, 1, . . . , k− 1} an edge coloring (or labeling) of G using k labels, where adjacent edges may be assigned the same label. For each vertex v of G, the color code of v with respect to c is the k-
Escuadro Henry E. +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular genetic markers and rubber breeding in Thailand : 2 - Field stndy of the family RRIM600 x PB217 for QTL identification [PDF]
, 2006 For developing QTL detection based on the genetic linkage map of the cross RRIM600 x PB217, a clonal field trial was set in Thailand in June 2002. It will be studied until 2010 and targeted to the genetic analysis of the physiological parameters of the ...
Clément-Demange, André +3 more
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Frontiers in Biomedical TechnologiesPurpose: Radiation shielding requires deep knowledge about the shielding materials properties. Additionally, the interaction between the radiation and materials should be well understood. Materials and Methods: Monte Carlo (MC) simulation, NXCOM, and
Nahid Makiabadi, Hosein Ghiasi
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Time Code for multifunctional 3D printhead controls
Nature CommunicationsDirect Ink Writing, an extrusion-based 3D printing technique, has attracted growing interest due to its ability to process a broad range of materials and integrate multifunctional printheads with features such as shape-changing nozzles, in-situ curing ...
Sarah Propst, Jochen Mueller
doaj +1 more source