Results 101 to 110 of about 14,154,114 (263)
Frontiers in Biomedical TechnologiesPurpose: Radiation shielding requires deep knowledge about the shielding materials properties. Additionally, the interaction between the radiation and materials should be well understood. Materials and Methods: Monte Carlo (MC) simulation, NXCOM, and
Nahid Makiabadi, Hosein Ghiasi
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
SATT: Tailoring code metric thresholds for different software architectures
, 2016 Code metric analysis is a well-known approach for assessing the quality of a software system. However, current tools and techniques do not take the system architecture (e.g., MVC, Android) into account. This means that all classes are assessed similarly,
Treude, Christoph (author) +21 more
core +2 more sources
Time Code for multifunctional 3D printhead controls
Nature CommunicationsDirect Ink Writing, an extrusion-based 3D printing technique, has attracted growing interest due to its ability to process a broad range of materials and integrate multifunctional printheads with features such as shape-changing nozzles, in-situ curing ...
Sarah Propst, Jochen Mueller
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Extracting and analyzing software code metrics from C# source code
, 2007 In many software engineering areas, such as software maintenance and software measurement, source code analysis plays a key role. It represents a fundamental step to acquire data that set up the basis for different kind of analyses.
Scotto M, Bianco M, Succi G
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
IBC (International Building Code) 2018
, 2018 xxvi,726hlm.;bib.;tab ...
INTERNATIONAL CODE COUNCIL
core
On the origin of the mitochondrial genetic code: Towards a unified mathematical framework for the management of genetic information [PDF]
, 2012 The origin of the genetic code represents one of the most challenging problems in molecular evolution. The genetic code is an important universal feature of extant organisms and indicates a common ancestry of different forms of life on earth.
Diego Luis Gonzalez +5 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source