ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt +76 more
wiley +1 more source
Calculating G-code for CNC machine using the Mamdani fuzzy logic inference system [PDF]
The widespread desire to automate the CNC machine control process and optimize it is leading to the development of new algorithms. The article presents both a novel approach to this task based on a fuzzy decision-making system as well as an evaluation of
Dawid Kalandyk +2 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Classifying Resolving Lists by Distances between Members
L Let $G$ be a connected graph and let $w_1,\cdots w_r$ be a list of vertices. We refer the choice of a triple $(r;G;w_1,\cdots w_r)$, as a {\em metric selection.} Let $\rho$ be the shortest path metric of $G$. We say that $w_1,\cdots w_r$ {\em resolves $
Paul Feit
doaj +1 more source
EGCL: an extended G-Code Language with flow control, functions and mnemonic variables [PDF]
In the context of computer numerical control (CNC) and computer aided manufacturing (CAM), the capabilities of programming languages such as symbolic and intuitive programming, program portability and geometrical portfolio have special importance -- They
Arroyave, S. +2 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Investigating 3 Axis CNC Processes for Creating 3D Objects [PDF]
Using 3 axis CNC (computer numerical code) routing processes of the Visualization Lab, the CNC was tested for 3D object milling. The CNC process was designed for manufacturing 2D cut out objects with or without a 3D surface.
Newsum, Michael Jake
core +1 more source
Exploiting graphic processing units parallelism to improve intelligent data acquisition system performance in JET's correlation reflectometer [PDF]
The performance of intelligent data acquisition systems relies heavily on their processing capabilities and local bus bandwidth, especially in applications with high sample rates or high number of channels.
Arcas Castro, Guillermo de +7 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Ultra-wide detuning planar Bragg grating fabrication technique based on direct UV grating writing with electro-optic phase modulation [PDF]
A direct UV grating writing technique based on phase-controlled interferometry is proposed and demonstrated in a silica-on-silicon platform, with a wider wavelength detuning range than any previously reported UV writing technology.
Gates, J.C. +6 more
core +1 more source

