Results 161 to 170 of about 9,409,602 (307)

Efficacy of chemotherapy with G-CSF versus plerixafor with G-CSF in autologous stem cell mobilization for lymphoma patients. [PDF]

Am J Cancer Res
Zhao J, Wen X, Ma L, Guo X, Su L.
europepmc   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Recombinant G-CSF-ApoAI Fusion Protein Is a Pleiotropic Factor. [PDF]

Molecules
Miroshnichenko S, Pykhtina M, Mosalev K, Beklemishev A, Beklemishev A.   +4 more
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

G-CSF for Mobilizing CD34⁺ Cells in Individuals With SCD: A Word of Caution. [PDF]

Am J Hematol
Sharma A, Abraham A, Bhatia M, Cancio M, Chaudhury S, Corbacioglu S, Guilcher GMT, Gupta AO, Hanna R, Heeney MM, John T, Krishnamurti L, LaBelle JL, Rangarajan HG, Shenoy S, Stenger E, Strunk C, Fitzhugh CD.   +17 more
europepmc   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Intraperitoneal G-CSF Stimulation Achieves Human-like Neutrophil Levels in NSG Mice Without Inducing Systemic Inflammation. [PDF]

Int J Mol Sci
Elrod R, Lu Y, Brochhausen C, Schönmehl R, Herrmann M, Zhang H, Mohr C, Ledermann Y, Blum L, Boettcher M, Klinke-Petrowsky M, Knopf J, Elrod J.   +12 more
europepmc   +1 more source

Targeting G-CSF to treat autoinflammation

Nature Immunology, 2023
Tom D. Bunney, Matilda Katan
openaire   +3 more sources

Randomized trial of sequential administration of G-CSF and GM-CSF versus G-CSF alone following peripheral blood progenitor cell autograft in solid tumors.

, 2000
A trial was conducted to investigate whether the sequential administration of recombinant human granulocyte colony-stimulating factor (G-CSF) and recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) could accelerate reconstitution ...
S. DE FILIPPIS, G. AMICONI, F. RECCHIA, M. GRIMALDI, T. BONFINI, M. ROSSELLI, P. ACCORSI, REA, Silvio, A. IACONE, G. CORRAO   +9 more
core  

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source