Results 251 to 260 of about 310,082 (306)

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

Use of Primary Prophylaxis with G-CSF in Acute Myeloid Leukemia Patients Undergoing Intensive Chemotherapy Does Not Affect Quality of Response. [PDF]

J Clin Med
Mezzanotte V, Paterno G, Cerroni I, De Marchi L, Taka K, Buzzatti E, Mallegni F, Meddi E, Moretti F, Buccisano F, Maurillo L, Palmieri R, Gurnari C, Venditti A, Del Principe MI.   +14 more
europepmc   +1 more source

Tumor-derived G-CSF induces an immunosuppressive microenvironment in an osteosarcoma model, reducing response to CAR.GD2 T-cells. [PDF]

J Hematol Oncol
Pezzella M, Quintarelli C, Quadraccia MC, Sarcinelli A, Manni S, Iaffaldano L, Ottaviani A, Ciccone R, Camera A, D'Amore ML, Di Cecca S, Sinibaldi M, Guercio M, Aurigemma M, De Falco P, Fustaino V, Rota R, Pomella S, Cassandri M, Di Giannatale A, Agrati C, Bordoni V, Guarracino F, Massa M, Del Baldo G, Becilli M, Milano GM, Del Bufalo F, Locatelli F, De Angelis B.   +29 more
europepmc   +1 more source

Effects of primary granulocyte colony-stimulating factor (G-CSF) prophylaxis for chemotherapy-induced febrile neutropenia in diffuse large B-cell lymphoma patients receiving the R-CHOP-21 regimen. [PDF]

Asian Biomed (Res Rev News)
Nakaphan P, Uaprasert N.
europepmc   +1 more source

Significant Reduction of Radiation-Induced Death in Mice Treated with PrC-210 and G-CSF after Irradiation. [PDF]

Radiat Res
Fahl WE, Fahl BL, Schult D, Goesch TR.
europepmc   +1 more source

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G-CSF

2008
Introduction: Zygomycosis is a life-threatening invasive fungal infection, occurring mostly among immunocompromised patients with profound neutropenia. Posaconazole is a novel antifungal triazole with activity against filamentous fungi, including zygomycetes.
openaire   +2 more sources

[G-CSF and G-CSF receptor].

Rinsho byori. The Japanese journal of clinical pathology, 1995
Relationship between leucocytosis and G-CSF blood concentration were examined. Increase in blood concentration of G-CSF of surgical patient and dialysis patient with leucocytosis were noticed. Determination of G-CSF receptor on leucocyte was performed by the flow cytometry using biotinylated G-CSF.
K, Saionji, T, Satoh, H, Tokuda, H, Watanabe, A, Ohsaka, K, Hiyoshi, W, Kurotani   +6 more
openaire   +1 more source

Kinetics of Autologous Stem Cell Mobilization Failure: Comparison of AMD3100/G-CSF, G-CSF, GM-/G-CSF, and Chemotherapy/G-CSF on Remobilization Success.

Blood, 2006
Abstract Background: No standard approach for the mobilization of peripheral hematologic stem and progenitor cells (HSPCs) has been established. High levels of circulating CD34+ cells, a surrogate marker for mobilization efficiency, are associated with less apheresis days.
John F. DiPersio, Angela Smith, Dianne Sempek, Albert Baker, Steven Jiang, Ravi Vij, Amanda Cashen, Peter Westervelt   +7 more
openaire   +1 more source

Sweet's syndrome associated with G‐CSF

British Journal of Haematology, 1993
Summary. Sweet's syndrome (SS) developed in two patients with acute myeloid leukaemia (AML) treated with granulocyte colony stimulating factor (G‐CSF) for febrile neutropenia due to AML chemotherapy. Fever, painful skin and conjunctival lesions developed and neutrophilic infiltration was detected at biopsy specimens.
Paydas S., Sahin B., Seyrek E., Soylu M., Gonlusen G., Acar A., Tuncer I.   +6 more
openaire   +3 more sources