Results 261 to 270 of about 9,409,602 (307)
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Editorial: Scrambling for a response to G-CSF
Journal of Leukocyte Biology, 2011Discussion on the implications of new mechanistic data on G-CSF effects on neutrophil differentiation.
Hal E, Broxmeyer, Ivo P, Touw
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Neuroprotection of G-CSF in Cerebral Ischemia
Frontiers in Bioscience, 2007In several experimental studies of cerebral ischemia, G-CSF exerts neuroprotective effects through different mechanisms, including mobilization of hematopoietic stem cells, anti-apoptosis, neuronal differentiation, angiogenesis and anti-inflammation. Hence, G-CSF not only inhibits neuron death, but also generates "new" neural tissue formation.
Chuan-Zhen, Lu, Bao-Guo, Xiao
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The interaction of G-CSF with its receptor
Frontiers in Bioscience, 2006The function of the G-CSF receptor has been of considerable interest, particularly because of the clinical usefulness of G-CSF. The first step in receptor activation, which is the interaction of G-CSF with its receptor, has been studied by mapping the binding sites of neutralizing antibodies, by studying the complexes formed between G-CSF and various ...
Judith E, Layton, Nathan E, Hall
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G-CSF - an anti-inflammatory cytokine-
Shock, 1995We have previously reported that in various macrophage populations prepared from G-CSF treated rats LPS-inducible TNF release was suppressed. In vitro, LPS induced liver cell death only when hepatocytes were cocultured with liver macrophages.
T. Hartung, H-D. Volk, A. Wendel
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Sterility of Filgrastim (G-CSF) in Syringes
Annals of Pharmacotherapy, 1996OBJECTIVE: To determine if the sterility of filgrastim (G-CSF) is maintained for up to 7 days when aseptically transferred from the vial to tuberculin syringes in a laminar air flow environment. DESIGN: The study was conducted in two ...
P A, Jacobson +4 more
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Nihon rinsho. Japanese journal of clinical medicine, 2016
In acute phase of ischemic stroke, as neuroprotective and neurogenerative role of granulocyte-colony stimulating factor(G-CSF), anti-apoptotic action, anti-inflammatory and anti-immune effect, and brain protective action against excitatory neurotoxicity have been reported.
Atsushi, Mizuma, Shunya, Takizawa
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In acute phase of ischemic stroke, as neuroprotective and neurogenerative role of granulocyte-colony stimulating factor(G-CSF), anti-apoptotic action, anti-inflammatory and anti-immune effect, and brain protective action against excitatory neurotoxicity have been reported.
Atsushi, Mizuma, Shunya, Takizawa
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Granulocyte transfusion in the G-CSF era
International Journal of Hematology, 2002Granulocyte transfusions have been used since the 1960s with varying degrees of clinical success in the treatment of infection in patients with neutropenia or inherited granulocyte disorders. A number of studies have indicated that efficacy may well be associated with the dose of granulocytes delivered. Collection of granulocytes using modern apheresis
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Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1997
G-CSF enhances the division, maturation and release of granulocyte precursor cells. The shortening of chemotherapy-induced leukopenia via G-CSF is well documented in literature, with fractionated radiotherapy alone one finds a distinct increase of the granulocyte level.
M, Riepl, R, Fietkau, R, Sauer
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G-CSF enhances the division, maturation and release of granulocyte precursor cells. The shortening of chemotherapy-induced leukopenia via G-CSF is well documented in literature, with fractionated radiotherapy alone one finds a distinct increase of the granulocyte level.
M, Riepl, R, Fietkau, R, Sauer
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Bulletin du cancer, 2006
Neutropenia and its subsequent infectious complications represent the most common dose-limiting toxicity of cancer chemotherapy. Febrile neutropenia (FN) occurs with common chemotherapy regimens in 25 to 40 % of treatment-naive patients, and its severity depends on the dose intensity of the chemotherapy regimen, the patient's prior history and ...
Frédéric, Viret +4 more
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Neutropenia and its subsequent infectious complications represent the most common dose-limiting toxicity of cancer chemotherapy. Febrile neutropenia (FN) occurs with common chemotherapy regimens in 25 to 40 % of treatment-naive patients, and its severity depends on the dose intensity of the chemotherapy regimen, the patient's prior history and ...
Frédéric, Viret +4 more
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G-CSF: filgrastim, lenograstim and biosimilars
Expert Opinion on Biological Therapy, 2014The identification, purification and molecular cloning of granulocyte colony-stimulating factor G-CSF in the 1980s; the nonclinical studies in the mid-1980s; and the subsequent development of G-CSF as a therapeutic agent in the late 1980s and 1990s have had a major influence on the treatment of many diseases.
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