Results 141 to 150 of about 12,884,416 (263)

Complementing Bone Mineral Density Assessment: DXA-Based Radiomics for Vertebral Evaluation in Older Adults. [PDF]

Medicina (Kaunas)
Concha-Cisternas Y, Guzmán-Muñoz E, Barrera-González D, Sepúlveda-Loyola W, Fernández-Huerta L, Cigarroa-Cuevas I, Yañez-Sepúlveda R, Montalva-Valenzuela F, Garcia-Carrillo E, Molina-Marquez I, Mello JB.   +10 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Relativistic Diffusing Particles, Entropy and Varying Cosmological Constants. [PDF]

Entropy (Basel)
Haba Z.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Quantum Thermodynamic Transformation Optics: A Unified Framework for Energy and Entropy With Application to the Casimir Force in Dissipative Metamaterials. [PDF]

Nanophotonics
Sadeghi MM, Sarısaman M.
europepmc   +1 more source

Entropy-based representation of image information

, 2002
Entropy-based representation of image ...
M Ferraro (13508533), G Boccignone (13508536), Terry Caelli (13062708)   +2 more
core  

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Inflammatory Syndrome Regulated by WNT/β-Catenin, Non-Muscle Myosin and α-SMA Is a Self-Organized Dissipative Structure. [PDF]

Biology (Basel)
Lecarpentier Y, Morini A, Locher C, Krokidis X.   +3 more
europepmc   +1 more source

ESTIMATING NON-PARAMETRIC AND PARAMETRIC TRANSFORMATION FUNCTIONS FROM SURVEY DATA: AN APPLICATION OF MINIMUM CROSS-ENTROPY [PDF]

A model of a (convex) technology of representative and non-representative firms in a heterogeneous sector is presented in non-parametric and parametric versions. The heterogeneity is specified with error terms.
Hoveid, Oyvind
core  

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source