Results 91 to 100 of about 15,493,584 (247)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Fixed point theorems of $G$-fuzzy contractions in fuzzy metric spaces endowed with a graph [PDF]

open access: yes, 2014
summary:Let $(X,M,\ast )$ be a fuzzy metric space endowed with a graph $G$ such that the set $V(G)$ of vertices of $G$ coincides with $X$. Then we define a $G$-fuzzy contraction on $X$ and prove some results concerning the existence and uniqueness of ...
Shukla, Satish
core   +3 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Estimates for the average scalar curvature of the Weil-Petersson metric on the moduli space M_g. [PDF]

open access: yes
. We give a precise estimate for the average scalar curvature of the Weil-Petersson metric on the moduli space Mg as g → ∞ up to the order 1/g ...
G. Schumacher, S. Trapani
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Statistical convergence in g-metric spaces

open access: yesFilomat, 2022
The purpose of this paper is to define statistically convergent sequences with respect to the metrics on generalized metric spaces (g-metric spaces) and investigate basic properties of this statistical form of convergence.
openaire   +3 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Dealing with non-metric dissimilarities in fuzzy central clustering algorithms [PDF]

open access: yes, 2008
Clustering is the problem of grouping objects on the basis of a similarity measure among them. Relational clustering methods can be employed when a feature-based representation of the objects is not available, and their description is given in terms of ...
Filippone, Maurizio   +2 more
core   +1 more source

Parabolic (φ, ξ, η, g, λ)-structures of second kind on hypersurfaces of dual metric 4-dimensional spaces

open access: yesLietuvos Matematikos Rinkinys, 2002
Parabolic metric (φ, ξ, η, g, λ)-structures of second kind on hypersurfaces of 4-dimensional dual metric space and its properties are investigated. Some examples of normal, integrable parabolic metric structures of second kind are given.
Angelė Baškienė
doaj   +3 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

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