Results 71 to 80 of about 16,590,082 (290)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Some Fixed point Theorems in Generalization Metric space [PDF]

open access: yes, 2014
In this paper we establish some fixed point results for mapping satisfying sufficient contractive conditions on a complete G-metric space.
Tiwari, Rashmi   +2 more
core  

Application of the Fisher-Rao metric to ellipse detection [PDF]

open access: yes, 2007
The parameter space for the ellipses in a two dimensional image is a five dimensional manifold, where each point of the manifold corresponds to an ellipse in the image. The parameter space becomes a Riemannian manifold under a Fisher-Rao metric, which is
Stephen J. Maybank, Maybank, Stephen J.
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Some New Common Fixed Point Theorems under Strict Contractive Conditions in G-Metric Spaces

open access: yesJournal of Applied Mathematics, 2012
We introduce some new types of pairs of mappings (𝑓,𝑔) on G-metric space called G-weakly commuting of type (𝐴𝑓) and G-R-weakly commuting of type (𝐴𝑓).
Zead Mustafa
doaj   +1 more source

The equivalent condition of G-asymptotic tracking property and G-Lipschitz tracking property

open access: yesOpen Mathematics, 2022
In this paper, we introduce the concepts of GG-Lipschitz tracking property and GG-asymptotic tracking property in metric GG-space and obtain the equivalent conditions of GG-asymptotic tracking property in metric GG-space.
Ji Zhanjiang
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Fixed Point of Order 2 on G-Metric Space

open access: yesInternational Journal of Analysis and Applications, 2013
In this article we introduce a new concept of fixed point that is fixed point of order 2 on G-metric space and some results are achieved.
Animesh Gupta
doaj   +2 more sources

The space of metric structures on hyperbolic groups [PDF]

open access: yes, 2022
We study the metric and topological properties of the space $\mathscr{D}(G)$ of left-invariant hyperbolic pseudometrics on the non-elementary hyperbolic group $G$ that are quasi-isometric to a word metric, up to rough similarity.
Oregón-Reyes, Eduardo
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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