Results 61 to 70 of about 15,493,584 (247)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Geodesics on the Momentum Phase Space with metric $^{{C}}{g}$

open access: yesUniversal Journal of Mathematics and Applications, 2018
In this paper, a system of the differential equations giving geodesics on the momentum phase space with pseudo Riemann metric $^{C}g$ of a Hamilton space is found by using the Euler Lagrange equations.
İsmet Ayhan
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Compact Riemannian Manifolds with Homogeneous Geodesics

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2009
A homogeneous Riemannian space (M = G/H,g) is called a geodesic orbit space (shortly, GO-space) if any geodesic is an orbit of one-parameter subgroup of the isometry group G. We study the structure of compact GO-spaces and give some sufficient conditions
Dmitrii V. Alekseevsky   +1 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

A cohomological characterisation of Yu's Property A for metric spaces

open access: yes, 2012
We introduce the notion of an asymptotically invariant mean as a coarse averaging operator for a metric space and show that the existence of such an operator is equivalent to Yu’s property A.
Wright, Nick   +2 more
core   +1 more source

Some Modified Fixed Point Results in V-Fuzzy Metric Spaces

open access: yesAdvances in Fuzzy Systems, 2019
The present research paper focuses on the existence of fixed point in V-fuzzy metric space. The presentation of V-fuzzy metric space in n-tuple encourages us to define different mapping in the symmetric V-fuzzy metric space. Here, the properties of fuzzy
Vishal Gupta   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Best Proximity Point for G-Generalized ζ-β-T Contraction

open access: yesInternational Journal of Analysis and Applications, 2023
In this paper, we find the best proximity point in G-metric spaces for G-generalized ζ-β-T contraction mappings and verify the existence and uniqueness of the best proximity point in the complete G metric space using the idea of an approximatively ...
Amit Duhan   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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