Results 41 to 50 of about 12,796 (278)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
A Sequential-Interval Optimal Sampling Strategy Based on Reliability Prediction Under Wiener Process
MathematicsFor satellite electronic components characterized by high reliability and long lifespan, achieving improved efficiency in reliability prediction is essential when only a limited amount of data is available.
Mengying Ren +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait +23 more
wiley +1 more source
Modified Courant-Beltrami penalty function and a duality gap for invex optimization problem
International Journal for Simulation and Multidisciplinary Design Optimization, 2019 In this paper, we modified a Courant-Beltrami penalty function method for constrained optimization problem to study a duality for convex nonlinear mathematical programming problems. Karush-Kuhn-Tucker (KKT) optimality conditions for the penalized problem
Hassan Mansur, Baharum Adam
doaj +1 more source
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
Ex-Post Full Surplus Extraction, Straightforwardly [PDF]
, 2005 Consider an estimate of the common value of an auctioned asset that is symmetric in the bidders' types. Such an estimate can be represented solely in terms of the order statistics of those types.
Ronald M. Harstad, Vlad Mares
core +3 more sources
Computing exact $D$-optimal designs by mixed integer second-order cone programming
, 2015 Let the design of an experiment be represented by an $s$-dimensional vector $\mathbf {w}$ of weights with nonnegative components. Let the quality of $\mathbf {w}$ for the estimation of the parameters of the statistical model be measured by the criterion ...
Harman, Radoslav, Sagnol, Guillaume
core +1 more source
Optimal two-level conjoint designs with constant attributes in the profile sets [PDF]
, 2010 We propose a simple strategy to construct D-, A-, G- and V-optimal two-level designs for rating-based conjoint studies with large numbers of attributes. In order to simplify the rating task, the designs hold one or more attributes at a constant level in ...
Goos, P.P. (Peter) +2 more
core +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter +17 more
wiley +1 more source
Mağallaẗ Al-kūfaẗ Al-handasiyyaẗ, 2019 This work contributes two novel modified Taguchi techniques to the optimal parametric setting for minimum water absorption in epoxy composites. Taguchi method, using ASTM standards was applied with factors (initial weight, final weight, length, sample ...
Oluwaseyi A. Ajibade +2 more
doaj +1 more source