Results 1 to 10 of about 1,404,567 (144)
Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics. [PDF]
Technol Cancer Res Treat, 2017 Protein instability is a major obstacle in the production and delivery of monoclonal antibody–based therapies for cancer. This study presents real-time isothermal differential scanning fluorimetry as an emerging method to evaluate the stability of human immunoglobulin G protein with high sensitivity.
Moggridge J +3 more
europepmc +5 more sources
G-stability one-leg hybrid methods for solving DAEs [PDF]
Advances in Difference Equations, 2019 This paper introduces the solution of differential algebraic equations using two hybrid classes and their twin one-leg with improved stability properties.
P. Agarwal +2 more
doaj +3 more sources
Molecules, 2021 Cells have evolved elaborate mechanisms to regulate DNA replication machinery and cell cycles in response to DNA damage and replication stress in order to prevent genomic instability and cancer. The E3 ubiquitin ligase SCFDia2 in S.
Aneliya Ivanova +6 more
doaj +1 more source
Biomedicines, 2021 Cells are constantly exposed to numerous mutagens that produce diverse types of DNA lesions. Eukaryotic cells have evolved an impressive array of DNA repair mechanisms that are able to detect and repair these lesions, thus preventing genomic instability.
Yordan Babukov +4 more
doaj +1 more source
On Sum and Stability of Continuous $G$-Frames [PDF]
Sahand Communications in Mathematical Analysis, 2020 In this paper, we give some conditions under which the finite sum of continuous $g$-frames is again a continuous $g$-frame. We give necessary and sufficient conditions for the continuous $g$-frames $Lambda=left{Lambda_w in Bleft(H,K_wright): win ...
Azam Yousefzadeheyni +1 more
doaj +1 more source
Cosmological stability in f(ϕ,G) gravity
Physics Letters B, 2023 In gravitational theories where a canonical scalar field ϕ with a potential V(ϕ) is coupled to a Gauss-Bonnet (GB) term G with the Lagrangian f(ϕ,G), we study the cosmological stability of tensor and scalar perturbations in the presence of a perfect ...
Shinji Tsujikawa
doaj +1 more source
On the equivalence of a-stability and g-stability [PDF]
Applied Numerical Mathematics, 1989 An algebraic result is obtained which enables the authors to establish the equivalence of \(A\)-stability and \(G\)-stability for one-leg methods. They obtain an alternative proof of the second Dahlquist barrier. In the following two of their results are stated: Theorem: If the polynomials \(\rho\) and \(\sigma\) are relatively prime, then \(A ...
Baiocchi, Claudio, Crouzeix, Michel
openaire +2 more sources
Binding-Induced Diversity of a Human Telomeric G-Quadruplex Stability Phase Space
Pharmaceuticals, 2022 The structural polymorphism of G-quadruplex nucleic acids is an important factor in their recognition by proteins and small-molecule ligands. However, it is not clear why the binding of several ligands alters G-quadruplex topology.
Domen Oblak +3 more
doaj +1 more source
Elongation factor G stabilizes the hybrid-state conformation of the 70S ribosome [PDF]
RNA, 2007 Following peptide bond formation, transfer RNAs (tRNAs) and messenger RNA (mRNA) are translocated through the ribosome, a process catalyzed by elongation factor EF-G. Here, we have used a combination of chemical footprinting, peptidyl transferase activity assays, and mRNA toeprinting to monitor the effects of EF-G on the positions of tRNA and mRNA ...
P Clint, Spiegel +2 more
openaire +2 more sources
Electronic Journal of Plant Breeding, 2022 Fifty four genotypes of greengram were investigated under four different environments in a randomised block design with three replications during the year 2021.
Kuldeep M. Akbari1*, Mukesh P. Patel2, Tejaskumar H. Borkhatariya1, Praful M. Sondarava1, Jay B. Delvadiya3
doaj +1 more source