Results 41 to 50 of about 11,933,284 (289)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The effect of oxidation on the stability of G-quadruplex DNA : implications for oncogene expression [PDF]

open access: yes, 2011
G-quadruplexes (G4-DNA) are a class of secondary structures formed from Guanine rich sequences. In recent years these structures have been implicated in both telomere maintenance and oncogene expression, and have been shown to be abundant in upstream ...
Stebbeds, William Joshua David
core  

Almost sure exponential stability of nonlinear stochastic delay hybrid systems driven by G-Brownian motion

open access: yesBoundary Value Problems, 2022
G-Brownian motion has potential applications in uncertainty problems and risk measures, which has attracted the attention of many scholars. This study investigates the almost sure exponential stability of nonlinear stochastic delay hybrid systems driven ...
Chao Wei
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Study of complexity factor and stability of dynamical systems in $$f(\mathcal {G})$$ f ( G ) gravity

open access: yesEuropean Physical Journal C: Particles and Fields
In this paper, we evaluate the complexity of the non static cylindrical geometry with anisotropic matter configuration in the framework of modified Gauss–Bonnet theory.
M. Zeeshan Gul   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

On the stability of generalized gamma functional equation

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2000
We obtain the Hyers-Ulam stability and modified Hyers-Ulam stability for the equations of the form g(x+p)=φ(x)g(x) in the following settings: |g(x+p)−φ(x)g(x)|≤δ,   |g(x+p)−φ(x)g(x)|≤ϕ(x),   |(g(x+p)/φ(x)g(x))−1|≤ψ(x).
Gwang Hui Kim
doaj   +1 more source

Stability analysis in fenugreek (Trigonella foenum-graecum L.)

open access: yesElectronic Journal of Plant Breeding, 2016
Thirty genotypes of fenugreek were grown at Instructional Farm, JAU, Junagadh in three different environments created by manipulating dates of sowing during rabi season of the year 2012-2013.
Jyoti Kumari   +2 more
doaj   +1 more source

Stability analyses of tef (Eragrostis tef [Zucc.] Trotter) grain yield in dryland areas of Northeast Ethiopia

open access: yesCogent Food & Agriculture, 2020
The Ethiopian cereal, tef, is a healthy food stuff for the people, and most preferred and palatable feed stuff for livestock. Evaluation of performance of genotypes at a number of locations provides useful information to determine their adaptation and ...
Fisseha Worede   +2 more
doaj   +1 more source

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