Results 111 to 120 of about 6,849,468 (275)

How OECD policies affected Latin America in the 1980s [PDF]

open access: yes
The authors assess the effects of OECD monetary and fiscal policies on Latin America by means of simulation studies using the LBS/NIESR Global Econometric Model and a new empirical model of Latin America.
Allen, Chris   +3 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Žvalgomieji tyrinėjimai T. Kosciuškos g. 3

open access: yes, 2008
2007 m. atlikti žvalgomieji archeologiniai tyrinėjimai ir archeologiniai žvalgymai Vilniaus piliakalnio su papiliais (A961K) teritorijoje, T. Kosciuškos g. 3 LNM saugyklų komplekse. 2006 m. šio komplekso saugyklų pastate 02 buvo atlikti žvalgomieji archeologiniai tyrinėjimai (žr. ATL 2006 metais, V., 2007, p. 385–386). 2007 m.
Steponaitis, Valdas, Vailionis, Evaldas
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Tyrinėjimai Kurpių g. 3

open access: yes, 2008
During 2007–2008 an evaluation was conducted in the basement of the large building at Kurpių st. 3 and beside it. The plot lies inside the territory of laipėda old town. 166 m2 was excavated during the evaluation. n the basis of the excavation, a preliminary analysis of the finds, and dendrochronological tests, we can survey in general terms the ...
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Sklypas Kurpių g. 3

open access: yes, 2009
During 2007–2008 an excavation (about 176 m2) was conducted on the plot at Kurpių St. 3 in Klaipėda Old Town. On the basis of the archaeological data, the preliminary analysis of the finds, and dendrochronological tests, it is possible to summarise the development of the quarter at Kurpių St. 3.
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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