Results 1 to 10 of about 94,078 (117)

Donanemab immunogenicity in participants with early symptomatic Alzheimer's disease [PDF]

Alzheimer’s & Dementia: Translational Research & Clinical Interventions
INTRODUCTION Donanemab is an immunoglobulin G1 antibody that targets an N‐terminal truncated form of amyloid beta present in mature plaques. Treatment‐emergent (TE) anti‐drug antibodies (ADAs) were quantified in donanemab‐treated participants from two ...
Garrett R. Mullins, Paul Ardayfio, Ivelina Gueorguieva, Greg Anglin, Jason Bailey, Laiyi Chua, Jennifer A. Zimmer, Cynthia D. Evans, Emel Serap Monkul Nery, Hong Wang, Rashna Khanna, Dawn A. Brooks, John R. Sims   +12 more
doaj   +2 more sources

Multi-omic profiling defines three distinct molecular subtypes of urothelial carcinoma with implications for precision therapy. [PDF]

Clin Transl Med
We developed three UC clusters, applicable for MIBC and NMIBC, which were validated using transcriptomic- and proteomic datasets. Publically available UC cell lines were assigned to the clusters, to have in vitro models representing each cluster. The clusters differ in molecular and biological signatures, with distinct prognostic and therapeutic ...
van Creij NCH, Tymoszuk P, Handle F, Seeber A, Sellemond T, Martowicz A, Comperat E, Wafa H, Ormanns S, Günther M, Parson W, Noeparast M, Santer FR, Subiela JD, Grivas P, Li R, Culig Z, Pichler R.   +17 more
europepmc   +2 more sources

Accuracy assessment of high-resolution terrain data produced from UAV images georeferenced with on-board PPK positioning [PDF]

Journal of the Bulgarian Geographical Society, 2023
In recent years, unmanned aerial vehicles (UAVs) have increased rapidly and successfully established themselves as a tool for the rapid collection of high-resolution images as baseline data in land cover studies and topographic mapping. In photogrammetry
Davis Dinkov
doaj   +3 more sources

Twitter Use in Hurricane Isaac and Its Implications for Disaster Resilience

ISPRS International Journal of Geo-Information, 2021
Disaster resilience is the capacity of a community to “bounce back” from disastrous events. Most studies rely on traditional data such as census data to study community resilience.
Kejin Wang, Nina S. N. Lam, Lei Zou, Volodymyr Mihunov   +3 more
doaj   +1 more source

Estimating the Impacts of Proximity to Public Transportation on Residential Property Values: An Empirical Analysis for Hartford and Stamford Areas, Connecticut

ISPRS International Journal of Geo-Information, 2021
Public transit infrastructure may increase residential property values by improving accessibility and reducing commute expenses in urban areas. Prior studies have investigated the impacts of the proximity to public transportation on property values and ...
Bo Zhang, Weidong Li, Nicholas Lownes, Chuanrong Zhang   +3 more
doaj   +1 more source

Watershed Drought and Ecosystem Services: Spatiotemporal Characteristics and Gray Relational Analysis

ISPRS International Journal of Geo-Information, 2021
This study explored the spatiotemporal characteristics of drought and ecosystem services (using soil conservation services as an example) in the YanHe Watershed, which is a typical water basin in the Loess Plateau of China, experiencing soil erosion ...
Jizhou Bai, Zixiang Zhou, Yufeng Zou, Bakhtiyor Pulatov, Kadambot H. M. Siddique   +4 more
doaj   +1 more source

A Data-Driven Quasi-Dynamic Traffic Assignment Model Integrating Multi-Source Traffic Sensor Data on the Expressway Network

ISPRS International Journal of Geo-Information, 2021
Static traffic assignment (STA) models have been widely utilized in the field of strategic transport planning. However, STA models cannot fully represent the dynamic road conditions and suffer from inaccurate assignment during traffic congestion.
Xing Zeng, Xuefeng Guan, Huayi Wu, Heping Xiao   +3 more
doaj   +1 more source

Study on Fractal Characteristics of Migration-Population Flow—Evidence from Egypt

ISPRS International Journal of Geo-Information, 2021
Population migration is a major event of optimizing the allocation of production factors and a key way to construct regional relations and promote spatial reconstruction.
Sidong Zhao, Xingping Wang, Zhishan Ma
doaj   +1 more source

Factors That Affect Spatial Data Sharing in Malaysia

ISPRS International Journal of Geo-Information, 2022
This paper examines the phenomena of the local government’s inadequate reaction to the national programme of geographical infrastructure for the effective sharing of spatial data in Malaysia. We investigate the determinants of sharing data for Malaysia’s
Qasim Hamakhurshid Hamamurad, Normal Mat Jusoh, Uznir Ujang   +2 more
doaj   +1 more source

Make It Simple: Effective Road Selection for Small-Scale Map Design Using Decision-Tree-Based Models

ISPRS International Journal of Geo-Information, 2022
The complexity of a road network must be reduced after a scale change, so that the legibility of the map can be maintained. However, deciding whether to show a particular road section on the map is a very complex process.
Izabela Karsznia, Karolina Wereszczyńska, Robert Weibel   +2 more
doaj   +1 more source