Identification and characterization of the elusive protein backbone of the immuno-dominant and species-specific Em2(G11) metacestode antigen of Echinococcus multilocularis [PDF]
Alveolar echinococcosis (AE) caused by Echinococcus multilocularis, is a severe zoonotic disease in humans. One of the major metacestode antigens of E. multilocularis is the Em2 or Em2(G11) native purified antigen.
Philipp A. Kronenberg +13 more
doaj +4 more sources
Identification of the key amino acid mutations in the PB2 and PA proteins of classical swine H1N1 influenza A virus in mammalian adaptation [PDF]
The classical swine (CS) H1N1 influenza virus, first isolated in 1930, is highly homologous to the 1918 Spanish influenza virus. CS H1N1 virus, which crossed the interspecies barrier to infect humans has become the dominantly prevalent strain in China’s ...
Xiuhui Wang +15 more
doaj +2 more sources
Characterization of a Novel P[25],G11 Human Group A Rotavirus [PDF]
ABSTRACT A novel rotavirus strain (Dhaka6) isolated from a 21-year-old Bangladeshi male patient was characterized by sequence analysis of its VP7 and VP4 gene segments. Phylogenetic analysis of the VP7 gene of the Dhaka6 strain revealed a common evolutionary lineage with porcine G11 rotavirus strains.
Mustafizur Rahman +6 more
openalex +3 more sources
Outbreak associated with Rotavirus G11,P[25] in Korea in 2018 [PDF]
We here report the first outbreak caused by rotavirus G11,P[25] in Korea in 2018, representing a case of re-assortment with pig-derived rotavirus. The genotype constellation was identical to the virus identified in Korea in 2012 as G11-P[25]-I12-R1-C1-M1-A1-N1-T1-E1-H1. The infection source was not known exactly but it must be considered infection from
Su‐Jin Chae +4 more
openalex +3 more sources
Reassortment of Human Rotavirus Gene Segments into G11 Rotavirus Strains
G11 rotaviruses are believed to be of porcine origin. However, a limited number of G11 rotaviruses have been recently isolated from humans in combination with P[25], P[8], P[6], and P[4]. To investigate the evolutionary relationships of these strains, we
Jelle Matthijnssens +10 more
doaj +3 more sources
P2Y2 and Gq/G11 control blood pressure by mediating endothelial mechanotransduction [PDF]
Elevated blood pressure is a key risk factor for developing cardiovascular diseases. Blood pressure is largely determined by vasodilatory mediators, such as nitric oxide (NO), that are released from the endothelium in response to fluid shear stress exerted by the flowing blood.
Shengpeng Wang +12 more
openalex +3 more sources
Gq/G11 oncogenic mutations promote PD-L1 expression and suppress tumor immunity
Uveal melanoma (UM) is the predominant form of eye cancer. The genes GNAQ and GNA11, encoding Gq and G11 respectively, are most frequently mutated in UM and are considered the major drivers of UM carcinogenesis by activating YAP.
Jingyan Dong +6 more
doaj +3 more sources
Exopolysaccharide of Anoxybacillus pushchinoensis G11 has antitumor and antibiofilm activities
Exopolysaccharides (EPS/EPSs) possess several various applications in the food and pharmaceutical industries. This study was performed to investigate the biological (antibiofilm and antitumor), rheological (temperature, shear rate, and density) and chemical (solubility, carbohydrate and protein content, composition, molecular weight, functional group ...
Berna Genc, Mesut Taskin, Ahmet Adiguzel
openaire +5 more sources
Characterization of 2S albumin allergenic proteins for anaphylaxis in common buckwheat
2S albumin (2SA) is responsible for anaphylaxis following consumption of buckwheat in allergic individuals. To reduce allergen incidents, characterization of 2SA polypeptides is prerequisite, thus was analyzed in this study. Of the five 2S albumin genes (
Tomoyuki Katsube-Tanaka +1 more
doaj +1 more source

