Results 21 to 30 of about 80,485 (247)

Binding kinetics, bias, receptor internalization and effects on insulin secretion in vitro and in vivo of a novel GLP‐1R/GIPR dual agonist, HISHS‐2001 [PDF]

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 10, Page 5938-5949, October 2025.
Abstract Aims The use of incretin analogues has emerged as an effective approach to achieve both enhanced insulin secretion and weight loss in Type 2 diabetes (T2D) patients. Agonists which bind and stimulate multiple receptors have shown particular promise.
Yusman Manchanda   +11 more
wiley   +2 more sources

Outbreak associated with Rotavirus G11,P[25] in Korea in 2018 [PDF]

open access: yesInfection & Chemotherapy, 2020
We here report the first outbreak caused by rotavirus G11,P[25] in Korea in 2018, representing a case of re-assortment with pig-derived rotavirus. The genotype constellation was identical to the virus identified in Korea in 2012 as G11-P[25]-I12-R1-C1-M1-A1-N1-T1-E1-H1. The infection source was not known exactly but it must be considered infection from
Su-Jin Chae   +4 more
openaire   +3 more sources

G11 Procedural Opportunities For Paediatric Trainees [PDF]

open access: yesArchives of Disease in Childhood, 2013
Aim Trainees in paediatrics are required to become competent at a number of practical procedures but often express concern at lack of opportunities. We aimed to survey the number of practical procedures undertaken in 3 months, in two level 3 neonatal units in Scotland, and how these opportunities are distributed amongst trainees.
D Cochran, K Wallace
openaire   +2 more sources

DOES THE OOSTERHOFF DICHOTOMY EXIST IN THE ANDROMEDA GALAXY? I. THE CASE OF G11 [PDF]

open access: yesThe Astrophysical Journal, 2013
23 pages, 14 figures, 4 tables. Fig. 10 (right panel) replaced.
Karen Kinemuchi   +12 more
openaire   +11 more sources

Characterization of 2S albumin allergenic proteins for anaphylaxis in common buckwheat

open access: yesFood Chemistry: Molecular Sciences, 2022
2S albumin (2SA) is responsible for anaphylaxis following consumption of buckwheat in allergic individuals. To reduce allergen incidents, characterization of 2SA polypeptides is prerequisite, thus was analyzed in this study. Of the five 2S albumin genes (
Tomoyuki Katsube-Tanaka   +1 more
doaj   +1 more source

Mechanical properties of low alloy high phosphorus weathering steel [PDF]

open access: yesJournal of Mining and Metallurgy. Section B: Metallurgy, 2015
Mechanical behaviour of two low alloy steels (G11 and G12) was studied with respect to different phosphorus contents. Tensile strength and yield strength increased while percentage elongation at fracture decreased on increasing phosphorus ...
Jena B.K., Gupta N., Singh B., Ahoo G.S.
doaj   +1 more source

Potential monoamine oxidase A inhibitor suppressing paclitaxel‐resistant non‐small cell lung cancer metastasis and growth

open access: yesThoracic Cancer, 2020
Background High expression of monoamine oxidase A (MAOA) in non‐small cell lung cancer (NSCLC) is related to epithelial‐mesenchymal transition (EMT) and the development of clinicopathological features of NSCLC.
Xiaoguang Yang   +8 more
doaj   +1 more source

Multiscale Fine Characterization of a Coal Pore–Fracture System Based on SEM, CT, and NMR in the Jingbian Block, Ordos Basin

open access: yesEnergies, 2023
To achieve an accurate and comprehensive characterization of the multiscale pore–fracture characteristics of Permian coal in the Jingbian Block, Ordos Basin, a combination of scanning electron microscopy (SEM), X-ray computed tomography (CT), and nuclear
Suping Zhao   +3 more
doaj   +1 more source

Forecasting stock price movement: new evidence from a novel hybrid deep learning model [PDF]

open access: yesJournal of Asian Business and Economic Studies, 2022
Purpose – This study explores whether a new machine learning method can more accurately predict the movement of stock prices. Design/methodology/approach – This study presents a novel hybrid deep learning model, Residual-CNN-Seq2Seq (RCSNet), to predict ...
Yang Zhao, Zhonglu Chen
doaj   +1 more source

There are four dynamically and functionally distinct populations of E-cadherin in cell junctions

open access: yesBiology Open, 2015
E-cadherin is a trans-membrane tumor suppressor responsible for epithelial cell adhesion. E-cadherin forms adhesive clusters through combined extra-cellular cis- and trans-interactions and intracellular interaction with the actin cytoskeleton.
Zahra Erami   +4 more
doaj   +1 more source

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