Results 141 to 150 of about 134,818 (221)

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

Experimental Physiology, Volume 111, Issue 3, Page 1524-1542, 1 March 2026.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted, Alex Aupetit, Karl Björling, Kristian Agmund Haanes, Susanne Syberg, Niklas Rye Jørgensen, Blanca I. Aldana, Hirotsugu Tsuchimochi, Mark T. Waddingham, Kristine Freude, James Todd Pearson, Lars Jørn Jensen   +11 more
wiley   +1 more source

Prevalence, Activity Limitations and Quality of Life in Patients With Non-Specific Neck Pain in Burundi: A Cross-Sectional Study [Letter]

Journal of Pain Research
Alicia Shi Yao Chee, Yuling Dong Wolfson Medical School, University of Glasgow, Glasgow, G12 8QQ, UKCorrespondence: Yuling Dong, Wolfson Medical School, University of Glasgow, Glasgow, G12 8QQ, UK, Email 2968879d@student.gla.ac ...
Chee ASY, Dong Y
doaj  

Impact of KRAS-G12 Mutations on the KRAS-GTP Bound Conformational Dynamics: Structure, Free Energy Barriers and Drugging Pockets. [PDF]

JACS Au
Hu Z, Sha Z, Martí J, Guo SJ, Tao SC.
europepmc   +1 more source

G12/G13 biology in energy metabolism

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2019
null Kim Sg, Koo Jh, Kim Th, Yang Ym, Park Sy, Joo Ms, Han Cy, Choi Cs   +7 more
openaire   +2 more sources

KRAS^G12/13 mutation modulates CRC outcomes via disrupting positive feedback between macrophage and CD4⁺ T cell. [PDF]

iScience
Yan X, Su J, Liu H, Yuan T, Zhong Y, Xie T, Wang Z.   +6 more
europepmc   +1 more source

Unveiling the correlations between benzoic acid content, key microbial genera, and metabolites during the storage and transportation of raw yak milk based on multi-omics analysis. [PDF]

Food Chem X
Guo Y, Zhang Y, Wang R, Li Y, Wang L, Shi C, Yu X, Ma J, Zhang W, Wang P, Wen P.   +10 more
europepmc   +1 more source

Influence of an MDP Salt-Based Surface Cleaner on Bond Strength to Saliva-Contaminated Dentin At Different Stages of a Self-Etch Adhesive Procedure: An In Vitro Pilot Study. [PDF]

J Adhes Dent
Müdüroğlu Adıgüzel R, Kerimova Köse L, Çakmak Aktan E, Arhun N.   +3 more
europepmc   +1 more source

Detection of G12 human rotaviruses in Nepal

Detection of G12 human rotaviruses in Nepal
Of 731 stool specimens collected from children with diarrhea in Kathmandu, Nepal, from August 2004 through July 2005, 170 (23.3%) tested positive for rotavirus. Reverse transcription-PCR, including a revised G12-specific primer set, identified 56 (32.9%) as G2P[4] and 39 (23.0%) as G12 with P[6], P[8], or P[4].
openaire   +1 more source

Response to Letter to the Editor re: a phase II study of intrapatient dose escalation of biweekly trifluridine/tipiracil plus bevacizumab for colorectal cancer (E-BiTS study): KRAS mutations in colorectal cancer patients receiving trifluridine/tipiracil plus bevacizumab: something to consider. [PDF]

ESMO Open
Wakabayashi M, Taniguchi H.
europepmc   +1 more source

Clinico-genomic characterization of RAS-mutant acute myeloid leukemia. [PDF]

Ann Hematol
Yuan R, Xie Y, Miron PM, Higgins AW, Hutchinson L, Cerny J, Patel SA.   +6 more
europepmc   +1 more source