Results 71 to 80 of about 127,909 (300)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Functional Analysis of a Critical Glycine (Glycine 12) in Beta-type Connexins of Human Skin [PDF]

open access: yes, 2020
At least five beta-type connexins are expressed in various layers of the skin (Cx26, Cx30, Cx30.3, Cx31, and Cx32) and all include a glycine residue at position 12.
Bailey, Rasheed
core   +1 more source

Immunochemical analysis of oat avenins in an oat cultivar and landrace collection [PDF]

open access: yes, 2020
Oats have been found to be tolerated by most celiac disease patients, and oats are generally considered a good and safe addition to the gluten-free diet.
Ahola, Hanna Gabriela   +5 more
core   +1 more source

Conformational Change in a Four‐Tetrad DNA G‐Quadruplex upon Intercalation of a Small‐Molecule Ligand PyDH2

open access: yesAngewandte Chemie, EarlyView.
An exception or the rule? This work represents a second observation, and the first crystallographic evidence, of true intercalation of a small‐molecule ligand (here, bisquinolinium PyDH2) into an antiparallel G‐quadruplex (G4) DNA fold. Abstract G‐quadruplexes (G4s) are non‐canonical DNA structures implicated in a number of biological processes.
Kailey N. Martin   +7 more
wiley   +2 more sources

The difference in the intraday return-volume relationships of spot and futures: a quantile regression approach

open access: yesEconomics: Journal Articles, 2019
This study illuminates the difference in the intraday return-volume relationships of spot and index futures. The quantile regression analyses show that the widening effect of the spot trading volume on the distribution of spot returns disappears within a
Lee Jaeram, Lee Geul, Ryu Doojin
doaj   +1 more source

Modeling Distress in US High Yield Mutual Funds Before and During the Covid-19 Pandemic

open access: yesFolia Oeconomica Stetinensia, 2022
Research background: In March 2020, when the US financial markets were in the grip of the COVID-19 crisis, the Fed instituted various policies and programs to alleviate stress in financial markets. One such program involved the Fed purchase of securities
Szymczyk Łukasz   +2 more
doaj   +1 more source

Moate Simulation of Stochastic Processes [PDF]

open access: yesarXiv, 2022
A novel approach called Moate Simulation is presented to provide an accurate numerical evolution of probability distribution functions represented on grids arising from stochastic differential processes where initial conditions are specified. Where the variables of stochastic differential equations may be transformed via It\^o-Doeblin calculus into ...
arxiv  

Influencia de las propiedades del material en la caracterización a cortadura intralaminar mediante la configuración de tabs oblicuos del ensayo off-axis a 10º [PDF]

open access: yes, 2001
IV CONGRESO NACIONAL DE MATERIALES COMPUESTOS. Celebrado en Gijón, los días 21,22 y 23 de Noviembre de 2001En este trabajo se considera el ensayo de tracción off-axis bajo la configuración de tabs oblicuos como procedimiento para la caracterización a ...
Cañas Delgado, José   +2 more
core  

Two-component Bose gases with one-body and two-body couplings [PDF]

open access: yes, 2013
We study the competition between one-body and two-body couplings in weakly-interacting two-component Bose gases, in particular as regards field correlations.
Dao, Tung-Lam   +3 more
core   +2 more sources

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

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