Galacto-Oligosaccharide RP-G28 Improves Multiple Clinical Outcomes in Lactose-Intolerant Patients [PDF]
Background and Aims: Lactose intolerance (LI) is a global problem affecting more than half of the world’s population. An ultra-purified, high-concentration galacto-oligosaccharide, RP-G28, is being developed as a treatment for patients with LI.
William D. Chey +5 more
semanticscholar +5 more sources
Fatty Acid Synthase Inhibitor G28 Shows Anticancer Activity in EGFR Tyrosine Kinase Inhibitor Resistant Lung Adenocarcinoma Models [PDF]
Epidermal growth factor receptor (EGFR) tyrosine kinases inhibitors (TKIs) are effective therapies for non-small cell lung cancer (NSCLC) patients whose tumors harbor an EGFR activating mutation. However, this treatment is not curative due to primary and
Emma Polonio‐Alcalá +8 more
semanticscholar +7 more sources
G28 Effective safety netting: an important contribution to avoiding preventable deaths [PDF]
Safety netting has conventionally been used during consultations when clinicians are uncertain about the trajectory of an illness to provide patients with guidance about when and where to re-consult (Roland et al 2013). Recent high profile events involving failure to recognise and appropriately safety net children with sepsis highlights this is a ...
SJ Neill +4 more
semanticscholar +3 more sources
G28(P) How can we improve induction to the paediatric and neonatal intensive care units? [PDF]
Background Our regional Paediatric and Neonatal Intensive Care Units (PICU and NICU) care for 1700 critically unwell children a year. Medical staffing is provided by senior paediatric or anaesthetic trainees, and overseas fellows from diverse professional backgrounds, starting at several different points throughout the year, completing rotations of 3 ...
M Emedo
semanticscholar +3 more sources
EGCG-Derivative G28 Shows High Efficacy Inhibiting the Mammosphere-Forming Capacity of Sensitive and Resistant TNBC Models [PDF]
Recent studies showed that Fatty Acid Synthase (FASN), a lipogenic enzyme overexpressed in several carcinomas, plays an important role in drug resistance.
Ariadna Giró‐Perafita +6 more
semanticscholar +8 more sources
G28 A Novel Missense Mutation in Keratin 1 Underlying Clinically Mild Epidermolytic Ichthyosis Mimicking Epidermolysis Bullosa Simplex Superficialis [PDF]
Inherited skin peeling may be autosomal recessive (AR) or autosomal dominant (AD). When AR, this can be localised, as in acral peeling skin syndrome (APSS); or generalised, as in peeling skin syndrome (PSS) types A (non-inflammatory) and B (inflammatory).
A. Mackenzie +8 more
semanticscholar +3 more sources
Construction, Expression, and Characterization of BD1-G28-5 sFv, a Single-chain Anti-CD40 Immunotoxin Containing the Ribosome-inactivating Protein Bryodin 1 [PDF]
The major limitation to the use of immunotoxins in the clinic is the toxicity associated with the toxin moiety. BD1-G28-5 single-chain Fv (sFv) is a single-chain immunotoxin targeted to human CD40 and consists of bryodin 1 (BD1), a plant ribosome ...
Joseph A. Francisco +2 more
semanticscholar +5 more sources
Improving lactose digestion and symptoms of lactose intolerance with a novel galacto-oligosaccharide (RP-G28): a randomized, double-blind clinical trial [PDF]
BackgroundLactose intolerance (LI) is a common medical problem with limited treatment options. The primary symptoms are abdominal pain, diarrhea, bloating, flatulence, and cramping.
Dennis A. Savaiano +7 more
semanticscholar +7 more sources
G28 ABPM in the trenches?An analysis of a six year experience with emphasis on practical aspects [PDF]
D SVAHN
semanticscholar +3 more sources

