Results 1 to 10 of about 21,548 (239)

Galacto-Oligosaccharide RP-G28 Improves Multiple Clinical Outcomes in Lactose-Intolerant Patients [PDF]

open access: goldNutrients, 2020
Background and Aims: Lactose intolerance (LI) is a global problem affecting more than half of the world’s population. An ultra-purified, high-concentration galacto-oligosaccharide, RP-G28, is being developed as a treatment for patients with LI.
William D. Chey   +5 more
semanticscholar   +5 more sources

Fatty Acid Synthase Inhibitor G28 Shows Anticancer Activity in EGFR Tyrosine Kinase Inhibitor Resistant Lung Adenocarcinoma Models [PDF]

open access: goldCancers, 2020
Epidermal growth factor receptor (EGFR) tyrosine kinases inhibitors (TKIs) are effective therapies for non-small cell lung cancer (NSCLC) patients whose tumors harbor an EGFR activating mutation. However, this treatment is not curative due to primary and
Emma Polonio‐Alcalá   +8 more
semanticscholar   +7 more sources

G28 Effective safety netting: an important contribution to avoiding preventable deaths [PDF]

open access: bronzeArchives of Disease in Childhood, 2015
Safety netting has conventionally been used during consultations when clinicians are uncertain about the trajectory of an illness to provide patients with guidance about when and where to re-consult (Roland et al 2013). Recent high profile events involving failure to recognise and appropriately safety net children with sepsis highlights this is a ...
SJ Neill   +4 more
semanticscholar   +3 more sources

G28(P) How can we improve induction to the paediatric and neonatal intensive care units? [PDF]

open access: goldBritish Association for Paediatric Nephrology and Paediatric Intensive Care Society, 2018
Background Our regional Paediatric and Neonatal Intensive Care Units (PICU and NICU) care for 1700 critically unwell children a year. Medical staffing is provided by senior paediatric or anaesthetic trainees, and overseas fellows from diverse professional backgrounds, starting at several different points throughout the year, completing rotations of 3 ...
M Emedo
semanticscholar   +3 more sources

EGCG-Derivative G28 Shows High Efficacy Inhibiting the Mammosphere-Forming Capacity of Sensitive and Resistant TNBC Models [PDF]

open access: goldMolecules, 2019
Recent studies showed that Fatty Acid Synthase (FASN), a lipogenic enzyme overexpressed in several carcinomas, plays an important role in drug resistance.
Ariadna Giró‐Perafita   +6 more
semanticscholar   +8 more sources

G28 A Novel Missense Mutation in Keratin 1 Underlying Clinically Mild Epidermolytic Ichthyosis Mimicking Epidermolysis Bullosa Simplex Superficialis [PDF]

open access: bronzeArchives of Disease in Childhood, 2013
Inherited skin peeling may be autosomal recessive (AR) or autosomal dominant (AD). When AR, this can be localised, as in acral peeling skin syndrome (APSS); or generalised, as in peeling skin syndrome (PSS) types A (non-inflammatory) and B (inflammatory).
A. Mackenzie   +8 more
semanticscholar   +3 more sources

Construction, Expression, and Characterization of BD1-G28-5 sFv, a Single-chain Anti-CD40 Immunotoxin Containing the Ribosome-inactivating Protein Bryodin 1 [PDF]

open access: hybridJournal of Biological Chemistry, 1997
The major limitation to the use of immunotoxins in the clinic is the toxicity associated with the toxin moiety. BD1-G28-5 single-chain Fv (sFv) is a single-chain immunotoxin targeted to human CD40 and consists of bryodin 1 (BD1), a plant ribosome ...
Joseph A. Francisco   +2 more
semanticscholar   +5 more sources

Improving lactose digestion and symptoms of lactose intolerance with a novel galacto-oligosaccharide (RP-G28): a randomized, double-blind clinical trial [PDF]

open access: goldNutrition Journal, 2013
BackgroundLactose intolerance (LI) is a common medical problem with limited treatment options. The primary symptoms are abdominal pain, diarrhea, bloating, flatulence, and cramping.
Dennis A. Savaiano   +7 more
semanticscholar   +7 more sources

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