Results 61 to 70 of about 208,134 (332)

AML‐Targeted Metal‐Polyphenol Nanoplatform Induces Ferroptosis‐ICD Cascade for Antitumor Immunity Boosting

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang   +9 more
wiley   +1 more source

Youth Financial Literacy Short Scale: Proposition and validation of a measure

open access: yesSocial Sciences and Humanities Open
We propose a short instrument for measuring financial literacy among young adults: Youth Financial Literacy Short Scale (YFLSS). An instrument with questions on financial knowledge, financial attitude, and financial behavior was applied with 1126 young ...
Ani Caroline Potrich   +2 more
doaj   +1 more source

Genotype 5 Japanese Encephalitis Virus—Old Genotype, New Threat

open access: yesZoonoses, 2022
Japanese encephalitis (JE) is an important viral encephalitis with epidemic status in Asia, which is caused by Japanese encephalitis virus (JEV), a member of the genus Flavivirus . JEV is divided into five genotypes.
Weijia Zhang   +3 more
doaj   +1 more source

Quasiphantom categories on a family of surfaces isogenous to a higher product

open access: yes, 2016
We construct exceptional collections of line bundles of maximal length 4 on $S=(C \times D)/G$ which is a surface isogenous to a higher product with $p_g=q=0$ where $G=G(32,27)$ is a finite group of order 32 having number 27 in the list of Magma library.
Kim, Hyun Kyu   +2 more
core   +1 more source

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin   +10 more
wiley   +1 more source

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

open access: yesAdvanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob   +12 more
wiley   +1 more source

Effect of zwitterions on electrochemical properties of oligoether-based electrolytes

open access: yes, 2015
Solid polymer electrolytes show great potential in electrochemical devices. Poly(ethylene oxide) (PEO) has been studied as a matrix for solid polymer electrolytes because it has relatively high ionic conductivity.
Forsyth, Maria   +5 more
core   +1 more source

Synergistic Sunlight‐Activated Photodynamic and Near‐Infrared‐Induced Mild Photothermal Therapy for Infected Wound Healing Using Functionalized Nano‐Bi2WO6 Composites

open access: yesAdvanced Science, EarlyView.
This work proposes a multifunctional Bi2WO6:Yb,Er@CuS@CS nanocomposite that integrates photodynamic therapy (PDT), near‐infrared‐triggered photothermal therapy (PTT), and Cu2+ release for infected wound repair. The nanocomposite demonstrates enhanced antibacterial efficacy via combined PDT, PTT, and Cu2+ release, effective immunomodulatory by mild ...
Yihao Sun   +9 more
wiley   +1 more source

Orthogonal multiplet bases in SU(Nc) color space

open access: yes, 2012
We develop a general recipe for constructing orthogonal bases for the calculation of color structures appearing in QCD for any number of partons and arbitrary Nc.
Keppeler, Stefan, Sjodahl, Malin
core   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

open access: yesAdvanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong   +13 more
wiley   +1 more source

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