Glucose-6-phosphate dehydrogenase status and risk of hemolysis in Plasmodium falciparum-infected African children receiving single-dose primaquine. [PDF]
, 2014 Glucose-6-phosphate dehydrogenase (G6PD) enzyme function and genotype were determined in Ugandan children with uncomplicated falciparum malaria enrolled in a primaquine trial after exclusion of severe G6PD deficiency by fluorescent spot test.
Bousema, Teun +9 more
core +4 more sources
Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model [PDF]
, 2015 The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries.
Bassat, Quique +19 more
core +7 more sources
3′-UTR variations and G6PD deficiency [PDF]
Journal of Human Genetics, 2013 The combination of two silent mutations, c.1311C>T in exon 11 and IVS11 T93C (glucose-6-phosphate dehydrogenase (G6PD) 1311T/93C), with unknown mechanism, have been reported in G6PD-deficient individuals in Asian populations including Malaysian aboriginal group, Negrito.
Farahnaz, Amini, Endom, Ismail
openaire +2 more sources
Cardiac Failure Associated With G6PD Deficiency [PDF]
Circulation Research, 2003 To the Editor: Jain et al1 made the very interesting suggestion that glucose-6-phosphate dehydrogenase (G6PD) deficiency contributes to cardiac dysfunction through increased susceptibility to oxidative injury and impairment of intracellular calcium transport in cardiomyocytes from rats.
Drent, M., Gorgels, A.P.M., Bast, A.
openaire +2 more sources
Malaria Journal, 2020 Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most prevalent inborn disorder. This X-chromosome-linked recessive disease affects more than 400 million people globally, and is associated with haemolytic anaemia after medication ...
Wonsig Lee +3 more
doaj +1 more source
Diabetology & Metabolic Syndrome, 2022 Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common human genetic abnormalities, with a high prevalence in Guangdong, China.
Aijing Xu +10 more
doaj +1 more source
Reactivity of Blood Samples Spotted onto Filter Papers in the WST-8 Method for Screening of G6PD Deficiency. [PDF]
, 2006 Deficiency of glucose-6-phosphate dehydrogenase (G6PD) causes acute hemolytic anemia triggered by oxidative drugs such as primaquine. It is therefore essential in malaria-endemic areas for malaria patients to be confirmed for their G6PD activity before ...
Arai, Meiji +3 more
core +1 more source
Glucose-6-phosphate-dehydrogenase deficiency as a risk factor in proliferative disorder development [PDF]
, 2009 Glucose-6-phosphate dehydrogenase (G6PD) is an important site of metabolic control in the pentose phosphate pathway (PPP) which provides reducing power (NADPH) and pentose phosphates.
Alessandra Pani +9 more
core +1 more source
Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.
, 2009 Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew +5 more
core +1 more source
Advanced Science, EarlyView.To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu +6 more
wiley +1 more source