Results 111 to 120 of about 1,989,070 (268)

Biometric Analyses of Yield, Oil and Protein Contents of Wheat (Triticum aestivum L.) Genotypes in Different Environments

open access: yesAgronomy, 2019
The objectives of this study were to investigate: (1) the effects of genotype, environment, and their interactions on the oil content (OC), protein content (PC) and grain yield (GY) of 25 varieties of winter wheat, (2) the correlations among these traits
Ankica Kondić-Špika   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Stability analysis for grain yield and yield components in chick pea (Cicer arietinum l.) [PDF]

open access: yesElectronic Journal of Plant Breeding, 2011
Twenty one advanced breeding lines selected from All India Coordinated trials and one local popular variety “annegiri’ werestudied over three years to identify high yielding stable genotypes.
P.J.M.Rao
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Effects of groundwater and tailings interaction on the mobility of Thallium and other potentially toxic elements in a decommissioned Pb-Zn mining site (Raibl mine, north-eastern Italian Alps) [PDF]

open access: yes
Mining activity at the Raibl district (northeastern Italian Alps) date back to 1320, reaching the peak production in the 20th century. Nearly 350,000 tons of lead-zinc (Pb- Zn) ore, primarily sphalerite (ZnS) and galena (PbS), were annually extracted ...
Marussi G.   +7 more
core  

Variability of Grain Protein Content in Improved Upland Rice Genotypes and Its Response to Locations [PDF]

open access: yesElectronic Journal of Plant Breeding, 2011
To search for genetic resources of high grain protein content in upland rice, the variability and genotype × location interaction ofthe protein content was studied by a field experiment.
Totok A.D.H., Suwarto, A. Riyanto, D. Susanti, N. Farid, I.N. Kantun, Suwarno and Shao-Hui Zheng
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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