Results 181 to 190 of about 3,548,700 (196)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Growth Differentiation Factor-15 in Diabetic Kidney and Cardiovascular Disease: Pathogenic Driver or Protective Modulator. [PDF]

Diabetes
Slika A, Noureddine M, Jomaa D, Abboud EE, Zaidan S, Azar S, Ziyadeh F, Njeim R, Eid AA.   +8 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Image feature embedding with a deep learning framework improves genome-wide association studies on dog endophenotypes. [PDF]

Sci Adv
E GX, Wang GD.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Bergamot Essential Oil Beverage: Preparation, Formulation Optimization, and Preliminary Evaluation of Antidepressant-like Effects in Mice Induced by Chronic Corticosterone Treatment. [PDF]

Foods
Yang Q, Zhang Z, Li Y.
europepmc   +1 more source

Nanostructure and Collagen-Stimulating Activity of Cationic Pentapeptide Lipopeptides. [PDF]

J Pept Sci
de Mello LR, Castelletto V, Seitsonen J, Hamley IW.   +3 more
europepmc   +1 more source

Author Correction: Predicting biomass global warming potential with FT-NIR spectroscopy. [PDF]

Sci Rep
Gyawali P, Shrestha B, Phanomsophon T, Posom J, Pornchaloempong P, Sirisomboon P, Shrestha BP, Funke A.   +7 more
europepmc   +1 more source

Additional Evidence Fails to Associate Variation in KCNE4 With Equine Anhidrosis. [PDF]

Anim Genet
Petersen JL, Finno CJ.
europepmc   +1 more source

Boson peak in covalent network glasses: Isostaticity and marginal stability. [PDF]

Proc Natl Acad Sci U S A
Mizuno H, Mori T, Baldi G, Minamitani E.
europepmc   +1 more source