Results 31 to 40 of about 3,049 (113)

Multimodal mass spectrometry imaging for plaque- and region-specific neurolipidomics in Alzheimer's disease mouse models. [PDF]

Nat Commun
Trinklein TJ, Rubakhin SS, Okyem S, Croslow SW, Asadian M, Sabitha KR, Lazarov O, Lam F, Sweedler JV.   +8 more
europepmc   +1 more source

Ganglioside GM2 induces epithelial-mesenchymal transition (EMT) in cancer cells in a MEK/ERK/Egr1-dependent transcriptional program. [PDF]

J Biol Chem
Khamrui E, Banerjee S, Ray S, Ray A, Mahata B, Das T, Ghosh Z, Biswas K.   +7 more
europepmc   +1 more source

Five-year analysis of efficacy and safety of a bidirectional AAV gene therapy in Tay-Sachs sheep. [PDF]

J Clin Invest
Taghian T, Gallagher J, Bertrand S, Baker WC, Lopez Mercado K, Benatti HR, Hall E, Lopez Y, McElroy A, McCarthy JT, Pulaparthi S, Fernau D, Mather S, Esteves S, Diffie E, Gross A, Lahey HG, Jiang X, Parsley E, Gately R, Prestigiacomo R, Johnson S, Taylor A, Bierfeldt L, Tuominen S, Koehler J, Gao G, Xie J, Su Q, King R, Gounis MJ, Anagnostakou V, Puri A, Batista AR, Sena-Esteves M, Martin DR, Gray-Edwards H.   +36 more
europepmc   +1 more source

Lipid pathways connecting maternal BMI with infant obesity risk. [PDF]

Sci Rep
George AD, Wang T, Duong T, Schooneveldt Y, Paul S, Olshansky G, Mansell T, Saffery R, Vuillermin P, Ponsonby AL, Burgner D, Barwon Infant Study Investigator Group, Burugupalli S, Meikle PJ.   +13 more
europepmc   +1 more source

Unique bifunctional α-sialidase/β-N-acetylgalactosaminidase from Bifidobacterium bifidum acting on the Sd^a antigen. [PDF]

J Biol Chem
Katoh T, Suzuki R, Kataoka S, Kawasaki J, Kamio K, Komeno M, Yoshioka S, Rasmussen AT, Kimura I, Katayama T, Ashida H.   +10 more
europepmc   +1 more source

CNS-targeted base editing of the major late-onset Tay-Sachs mutation alleviates disease in mice. [PDF]

J Clin Invest
Allende ML, Kono M, Lee YT, Olmsted SM, Huso V, Bakir JY, Pratto F, Li C, Byrnes C, Tuymetova G, Zhu H, Tifft CJ, Proia RL.   +12 more
europepmc   +1 more source

Sphingolipids in Gaucher disease: a systematic review. [PDF]

Orphanet J Rare Dis
Lake A, Fuller M.
europepmc   +1 more source

Interplay of SLC33A1-dependent and -independent Golgi sialic acid O-acetylation in CASD1 catalysis. [PDF]

Nat Commun
Albers M, Bosse L, Schröter L, Junemann AT, Rossdam C, Hartmann M, Grove M, Litfin T, Egger AS, Kwiatkowski M, Thedieck K, Zocher G, Buettner FFR, Malde AK, von Itzstein M, Mühlenhoff M.   +15 more
europepmc   +1 more source

Generation of mice with combined Hexa Gly269Ser KI or KO and Neu3 KO alleles to create new models of GM2 gangliosidoses. [PDF]

Biol Open
Barker EN, Ashiri M, Saville JT, Hemming R, Furletti N, Dhume SH, Yu S, Anjos E, Wu X, Fresnoza A, Merz DC, Jackson M, Del Bigio MR, Siddiqui TJ, Fuller M, Mark BL, Triggs-Raine B.   +16 more
europepmc   +1 more source

Constraint-based modelling of metabolic dysregulation in Gaucher disease: mitochondrial dysfunction and disrupted cholesterol homeostasis. [PDF]

Orphanet J Rare Dis
Liu Y, Luo X, Ranjbar S, Aerts JMFG, van der Lienden M, Dardis A, Fleming RMT.   +6 more
europepmc   +1 more source