Gadolinium-based MRI contrast agent for the detection of tyrosinase
The Analyst, 2020 We successfully designed and synthesized a tyrosinase-targeting Gd( iii )-based MR contrast agent. The probe shows enhanced T 1 relaxation rate in the presence of tyrosinase in artificial cerebral spinal fluid.
Hyewon Seo, Heather A. Clark
openaire +3 more sources
Trends in Gadolinium-Based Contrast Agents Use in Radiology Practice: A Retrospective Evaluation
Objective: Contrast refers to the difference in signal strength in magnetic resonance imaging (MRI) that makes it possible to distinguish between different tissues. Contrast agents used in MRI can highlight the differences between tissues and organs, and
Ozlem Celik Aydin, Huseyin Aydemir
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A Review on the Design of Carbon-Based Nanomaterials as MRI Contrast Agents
MoleculesThe administration of magnetic resonance imaging (MRI) contrast agents (CAs) has been conducted since 1988 by clinicians to enhance the clarity and interpretability of MR images.
Sarah Garifo +3 more
doaj +1 more source
Retention of Gadolinium in Cerebrospinal Fluid and Decreased Renal Function: A Case Report
대한영상의학회지, 2017 A gadolinium-based contrast is the preferred agent when differentiating acute neurological diseases. Since the renal route is the main pathway for excretion of gadolinium chelates, prolonged extracellular distribution of gadolinium has previously been ...
Kyeong Sik Park +5 more
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Dynamic Quantitative T1 Mapping in Orthotopic Brain Tumor Xenografts
Translational Oncology, 2016 Human brain tumors such as glioblastomas are typically detected using conventional, nonquantitative magnetic resonance imaging (MRI) techniques, such as T2-weighted and contrast enhanced T1-weighted MRI.
Kelsey Herrmann +7 more
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Peptide-Based Soft Hydrogels Modified with Gadolinium Complexes as MRI Contrast Agents
Pharmaceuticals, 2020 Poly-aromatic peptide sequences are able to self-assemble into a variety of supramolecular aggregates such as fibers, hydrogels, and tree-like multi-branched nanostructures.
Enrico Gallo +5 more
doaj +1 more source
Inductively coupled plasma with mass-spectrometry method development and validation for gadolinium in gadolinium-based contrast agents of pharmaceutical formulations [PDF]
, 2020 Gadolinium-based contrast agent interacts with the human body temporarily and improves the pictures of inside of the body produced by magnetic resonance imaging, computed tomography, X-rays and ultrasound and it also helps to distinguish the normal from ...
Kona, Subramanya Srinivas +3 more
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Gadolinium-Based MRI Contrast Agents Induce Mitochondrial Toxicity and Cell Death in Human Neurons, and Toxicity Increases With Reduced Kinetic Stability of the Agent. [PDF]
, 2019 OBJECTIVES This preclinical study was devised to investigate potential cellular toxicity in human neurons induced by gadolinium-based contrast agents (GBCAs) used for contrast-enhanced magnetic resonance imaging (MRI).
von Tengg-Kobligk, Hendrik +4 more
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, 2019 Hydroxyapatite nanoparticles have drawn much attention in the development of multifunctional nanosystems because of their excellent biocompatibility. In the report, gadolinium-doped hydroxyapatite nanorods (NHA:Gd) were controlled synthesized through ...
Jing Sun (141206) +7 more
core +1 more source
Biocompatible Polyhydroxyethylaspartamide-based Micelles with Gadolinium for MRI Contrast Agents
Nanoscale Research Letters, 2010 Biocompatible poly-[N-(2-hydroxyethyl)-d,l-aspartamide]-methoxypoly(ethyleneglycol)-hexadecylamine (PHEA-mPEG-C16) conjugated with 1,4,7,10-tetraazacyclododecan-1,4,7,10-tetraacetic acid-gadolinium (DOTA-Gd) via ethylenediamine (ED) was synthesized as a ...
Kim Hyo Jeong +8 more
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