Results 41 to 50 of about 202,711 (324)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
The variability processing and analysis of the Gaia mission
, 2014 We present the variability processing and analysis that is foreseen for the Gaia mission within Coordination Unit 7 (CU7) of the Gaia Data Processing and Analysis Consortium (DPAC). A top level description of the tasks is given.Comment: 4 pages, 1 figure.
Clementini, Gisella +12 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Abdominal Wall Hernias in Peritoneal Dialysis Patients: Risk Factors and Technique Survival
Revista Portuguesa de Nefrologia e Hipertensão, 2023 Introduction: Peritoneal dialysis patients are at increased risk of developing abdominal wall complications, including hernias. This study aimed to determine the incidence of hernias in peritoneal dialysis patients, identify risk factors, and evaluate ...
Daniela Alfere +8 more
doaj +1 more source
The Gaia satellite: a tool for Emission Line Stars and Hot Stars [PDF]
, 2008 The Gaia satellite will be launched at the end of 2011. It will observe at least 1 billion stars, and among them several million emission line stars and hot stars. Gaia will provide parallaxes for each star and spectra for stars till V magnitude equal to
Alecian, Evelyne +21 more
core +3 more sources
, 2017 Recently, the first installment of data from ESA's Gaia astrometric satellite mission (Gaia-DR1) was released, containing positions of more than 1 billion stars with unprecedented precision, as well as only proper motions and parallaxes, however only for
Altmann, Martin +4 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Assessing the Contribution of Urban Freight Terminals in Last Mile Operations
Transport and Telecommunication, 2016 This paper introduces a multi-stakeholder multi-criteria evaluation framework, which can be used for the assessment of the last mile distribution performance of urban freight terminals.
Nathanail Eftihia +2 more
doaj +1 more source
Using Java for distributed computing in the Gaia satellite data processing [PDF]
, 2011 In recent years Java has matured to a stable easy-to-use language with the flexibility of an interpreter (for reflection etc.) but the performance and type checking of a compiled language.
Hernandez, Jose +5 more
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source