Results 81 to 90 of about 59,243 (307)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Cerámica: Comuninidad de Puerto Colombia (Río Tiquié - Vaupés)

open access: yes, 2020
El video documenta el proceso de la cerámica en la comunidad Puerto Colombia, en el Vaupés.El arte de la cerámica como actividad tradicional de las mujeres de la comuninidad Puerto Colombia.
Fundación GAIA AMAZONAS
core  

The Sci-GaIA project at the ICTP SciFabLab Workshop

open access: yes, 2015
The video has been recorded during the workshop "FabLab and Makerspaces for Science" held on 5-7 October 2015 at the Scientific Fabrication Laboratory (SciFabLab) of the Abdus Salam International Centre for Theoretical Physics (ICTP).
The Sci-GaIA Consortium
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Proceedings of the Sci-GaIA Workshop on "Promoting Open Science in Africa"

open access: yes, 2016
The joint Sci-GaIA-TANDEM-MAGIC workshop on "Promoting Open Science in Africa" was organised with the support of the European Commission (EC, DG CONNECT) and in conjunction with the WACREN 2016 Conference.
The Sci-GaIA Consortium
core   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Recensione a Mariano Croce "Bruno Latour. Irriduzionismo. Attante. Piattezza. Ibridi. Gaia"

open access: yes, 2022
Con il volume Bruno Latour Mariano Croce inaugura, per l’editore DeriveApprodi, Essentials, collana che ha l’intento di presentare, attraverso cinque concetti chiave, il pensiero di alcuni autori fondamentali per il dibattito politico contemporaneo.
Eugenia Gaia, Esposito
core  

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