Results 41 to 50 of about 190,842 (249)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Implementation of Flat Gain Broadband Power Amplifier With Impedance Rotation Compensation

open access: yesIEEE Access, 2019
The conventional broadband impedance matching network in low-pass structure cannot present adequate broadband impedance rotation for the optimum broadband operation of the power amplifier (PA), resulting in performance variations and degradations.
Xiangyu Meng   +5 more
doaj   +1 more source

Digital Offset Calibration of an OPAMP Towards Improving Static Parameters of 90 nm CMOS DAC [PDF]

open access: yes, 2014
In this paper, an on-chip self-calibrated 8-bit R-2R digital-to-analog converter (DAC) based on digitally compensated input offset of the operational amplifier (OPAMP) is presented.
Arbet, D.   +3 more
core  

Coherent power combination of two Master-oscillator-power-amplifier (MOPA) semiconductor lasers using optical phase lock loops [PDF]

open access: yes, 2007
Using heterodyne Optical Phase-Locked Loops (OPLLs), two 1W high power 1550 nm master-oscillator-power-amplifier (MOPA) semiconductor lasers operating as current controlled oscillators are phase-locked to a 1 mW reference laser.
Aflatouni, Firooz   +7 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The Influence and Compensation of Microwave Holographic Measurement Errors on Antenna Measurement Accuracy

open access: yesApplied Sciences
Microwave holographic measurement technology is a common method used in antenna measurement. This method has high measurement efficiency and high precision.
Yongqing Zhao   +4 more
doaj   +1 more source

Compensation in Medical Research

open access: yesVoices in Bioethics, 2020
INTRODUCTION When reviewing research protocols, Institutional Review Board (IRB) members determine whether an investigator has selected an appropriate level of compensation for study participants.
Amie Devlin
doaj   +1 more source

On the calibration of direct-current current transformers [PDF]

open access: yes, 2014
Modern commercial direct-current current transformers (DCCT) can measure currents up to the kA range with accuracies better than 1E-5. We discuss here a DCCT calibration method and its implementation with commercial instruments typically employed in low ...
Callegaro, Luca   +2 more
core   +2 more sources

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Composite pulses for high-fidelity population inversion in optically dense, inhomogeneously broadened atomic ensembles [PDF]

open access: yes, 2016
We derive composite pulse sequences that achieve high-fidelity excitation of two-state systems in an optically dense, inhomogeneously broadened ensemble.
Demeter, Gabor
core   +2 more sources

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