Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Confidence-Guided Adaptive Diffusion Network for Medical Image Classification. [PDF]
J ImagingYan Y, Xie Z, Huang W.
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
A Power-Aware 5G Network Slicing Scheme for IIoT Systems with Age Tolerance. [PDF]
Sensors (Basel)Weng M, Bai Y, Xie X.
europepmc +1 more source
Toward Energy-Efficient and Low-Carbon Intrusion Detection in Edge and Cloud Computing Based on GreenShield Cybersecurity Framework. [PDF]
Sensors (Basel)Alshammari A.
europepmc +1 more source
Dynamic power and frequency domain allocation for dedicated sensing signals in downlink ISAC. [PDF]
Sci RepAman M +5 more
europepmc +1 more source
Research on cloud-edge-end distributed collaborative computing based on deep reinforcement learning. [PDF]
Sci RepWu C +5 more
europepmc +1 more source
Deformable Pyramid Sparse Transformer for Semi-Supervised Driver Distraction Detection. [PDF]
Sensors (Basel)Zhao Q +6 more
europepmc +1 more source