Results 41 to 50 of about 2,248,301 (258)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Analyzing a four quadrant dc-dc Luo converter by means of signal flow graph modeling technique

open access: yesAin Shams Engineering Journal, 2018
In this paper, the signal flow graph technique and Mason gain formula are applied for extracting small signal model and transfer functions from control to output and from input to output.
Ebrahim Babaei   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

On Pathos Semitotal and Total Block Graph of a Tree [PDF]

open access: yes, 2011
The concept of pathos of a graph G was introduced by Harary [2], as a collection of minimum number of line disjoint open paths whose union is G. The path number of a graph G is the number of paths in pathos.
Muddebihal M. H.
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Graph Topologies, Gap Metrics and Robust Stability for Nonlinear Systems

open access: yes, 2005
Graph topologies for nonlinear operators which admit coprime factorisations are defined w.r.t. a gain function notion of stability in a general normed signal space setting.
Bian, Wenming, French, Mark
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Trends in achieving nutritional status aged 0-23 months based on the TB/U index against the median line for 2019-2022 in Madina Regency

open access: yesJurnal Ilmiah Kesehatan
Child growth trends are used to compare weight gain and body length or height with standard weight gain and body length or height gain. Based on data from the 2021 Indonesian Nutrition Status Survey (SSGI) in North Sumatra Province in Madina Regency ...
Yessi Septia Tampubolon   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Promise and Limitations of Supervised Optimal Transport-Based Graph Summarization via Information Theoretic Measures

open access: yesIEEE Access, 2023
Graph summarization is the problem of producing smaller graph representations of an input graph dataset, in such a way that the smaller compressed graphs capture relevant structural information for downstream tasks.
Sepideh Neshatfar   +2 more
doaj   +1 more source

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