Results 61 to 70 of about 2,248,301 (258)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Occupancy probabilities in superintegrable bosonic networks
Nuclear Physics BWe associate a bosonic network to each complete bipartite graph. A Hamiltonian is defined with hopping terms on the edges of the graph, and a global interaction term depending on the vertex sets.
Lachlan Bennett +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The NEPS of Gain Graphs over Arbitrary Groups and its Spectra [PDF]
Advances in Group Theory and ApplicationsWe provide two definitions for a gain function on a non-complete extended p-sum (NEPS) of gain graphs over arbitrary groups. In the first one, the gain function takes values in the direct product of the gain groups of the factors.
Matteo Cavaleri +2 more
doaj +1 more source
Triple Connected Domination Number of a Graph [PDF]
, 2012 The concept of triple connected graphs with real life application was introduced by considering the existence of a path containing any three vertices of a graph G.
Selvam Avadayappan +7 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Meningkatkan Kemampuan Bekerja dengan Grafik melalui Pembelajaran Kinematika
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2019 : This research examines the increase of students’ ability in working with graph. This research is conducted by involving 58 students in class X SMA Negeri 5 Malang as the subjects.
Nurul Hidayah +2 more
doaj +1 more source
Graph Algorithm Animation with Grrr [PDF]
, 2000 We discuss geometric positioning, highlighting of visited nodes and user defined highlighting that form the algorithm animation facilities in the Grrr graph rewriting programming language. The main purpose of animation was initially for the debugging and
Peter J. Rodgers +3 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source