Results 21 to 30 of about 3,475 (159)
Radiation Oncology, 2021 Purpose Stereotactic body radiotherapy (SBRT) is increasingly used for treatment of liver tumors but the effect on metabolic liver function in surrounding tissue is largely unknown.
Michael Sørensen +4 more
doaj +1 more source
Two siblings with galactose mutarotase deficiency: Clinical differences
JIMD Reports, 2022 Galactose mutarotase (GALM) deficiency is an inherited metabolic disease caused by the deficiency of the first enzyme in the Leloir pathway. GALM deficiency was first reported in 2018. To date, eight cases have been reported.
Havva Yazici +4 more
doaj +1 more source
A presença da Galactoquinase em Tecidos Animais
Brazilian Archives of Biology and Technology, 2001 O autor relata trabalhos experimentais que o levaram a concluir pela existência da galactoquinase em tecidos animais, explicando desta maneira, que a primeira fase do metabolismo intermediário da galactose nos mesmos é a sua esterificação, em presença do
Metry Bacila
doaj +1 more source
Altered expression response upon repeated gene repression in single yeast cells.
PLoS Computational Biology, 2022 Cells must continuously adjust to changing environments and, thus, have evolved mechanisms allowing them to respond to repeated stimuli. While faster gene induction upon a repeated stimulus is known as reinduction memory, responses to repeated repression
Lea Schuh +6 more
doaj +1 more source
Proteomic analysis of Bifidobacterium longum subsp. infantis reveals the metabolic insight on consumption of prebiotics and host glycans. [PDF]
PLoS ONE, 2013 Bifidobacterium longum subsp. infantis is a common member of the intestinal microbiota in breast-fed infants and capable of metabolizing human milk oligosaccharides (HMO).
Jae-Han Kim +5 more
doaj +1 more source
BMC Pediatrics, 2002 Background The objective of this study was to document the clinical, laboratory and genetic features of galactosemia in patients from the Cape Town metropolitan region.
Brown Ruth +3 more
doaj +1 more source
A novel c.-22T>C mutation in
BMC Medical Genetics, 2009 Background Many genetic variations of GALK1 have been identified in the patients with galactokinase (GALK1) deficiency. However, the molecular characteristics of GALK1 in individuals with elevated GALK1 activity are relatively unknown.
Kim Jin Q +5 more
doaj +1 more source
The anomeric specificity of yeast galactokinase [PDF]
Archives of Biochemistry and Biophysics, 1965 Abstract In order to investigate the specificity of yeast galactokinase toward the α- and β-anomers of galactose, a chromatographic system has been developed for separating and identifying α- and β-galactose-1-phosphates. The purified enzyme was incubated with β-galactose, and the phosphorylated product was isolated and identified as α-Gal-1-P ...
S M, HOWARD, M R, HEINRICH
openaire +2 more sources
The unfolded protein response has a protective role in yeast models of classic galactosemia
Disease Models & Mechanisms, 2014 Classic galactosemia is a human autosomal recessive disorder caused by mutations in the GALT gene (GAL7 in yeast), which encodes the enzyme galactose-1-phosphate uridyltransferase.
Evandro A. De-Souza +6 more
doaj +1 more source
BioTechniques, 2004 The reverse two-hybrid system has been developed to readily identify molecules or mutations that can disrupt protein-protein interactions in vivo. This system is generally based on the interaction-dependent activation of a reporter gene, whose product ...
Tea Gunde +4 more
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