Results 101 to 110 of about 4,175 (247)

Sensitization of Non‐M3 Acute Myeloid Leukemia Blasts to All‐Trans Retinoic Acid by the LSD1 Inhibitor Tranylcypromine: TRANSATRA Phase I Study

European Journal of Haematology, EarlyView.
ABSTRACT The treatment of elderly, nonfit acute myeloid leukemia (AML)/MDS patients with relapsed/refractory (R/R) disease remains challenging. As histone demethylase LSD1 (KDM1A) is a rational therapeutic target in AML, we conducted a phase I trial (“rolling‐six design”) with the LSD1 inhibitor tranylcypromine (TCP, dose levels [DL] 20, 40, 60, 80 mg ...
Michael Kruszewski, Claudia Schmoor, Tobias Berg, Usama‐Ur Rehman, Marcus Schittenhelm, Katharina Götze, Andrea Kündgen, Caroline Pabst, Tobias Ma, Anna Frey, Julia Stomper, Dietmar Pfeifer, Eric Metzger, Johannes Jung, Kevin Moschallski, Johanna Thomas, Gesine Bug, Justus Duyster, Manfred Jung, Roland Schüle, Ralph Wäsch, Olga Grishina, Michael Lübbert   +22 more
wiley   +1 more source

"Fermi" bubbles are bursting from our galaxy. Their origins remain a mystery. [PDF]

Proc Natl Acad Sci U S A, 2023
Mann A.
europepmc   +1 more source

Broad-band and H surface photometry of the central regions of nearby active galaxies -- I. Observations [PDF]

, 2000
M. ́Sanchez‐Portal, Á. I. Díaz, R. Terlevich, E. Terlevich, M. A. Alvarez, I. Aretxaga   +5 more
openalex   +1 more source

Factors affecting the mean electrical axis of the heart in trained Thoroughbreds

Equine Veterinary Education, EarlyView.
Summary Background Assuming that the ventricular myocardium of horses is subjected to exercise‐induced hypertrophy, we hypothesised that the mean electrical axis (MEA) of the heart would change. Objectives To define a longitudinal study to detect any changes in the direction of the MEA in Thoroughbred horses using ECG.
M. Felici, P. Pratelli, A. Gazzano, F. Cecchi, G. Incastrone, N. Bernabò, P. Baragli   +6 more
wiley   +1 more source

Status of the ΛCDM theory: supporting evidence and anomalies. [PDF]

Philos Trans A Math Phys Eng Sci
Peebles PJE.
europepmc   +1 more source

Monitoring of active galactic nuclei. V. The Seyfert 1 galaxy Markarian 279

, 1993
G. M. Stirpe
openalex   +2 more sources

ABSTRACTS

Precision Radiation Oncology, EarlyView.
wiley   +1 more source

Emotional (Dis/Un)entanglement in Becoming an Academic in the Neoliberal Era: Dialogising Transnational Accounts of Being, Thinking and Feeling

International Journal of Applied Linguistics, EarlyView.
ABSTRACT This paper explores the complex emotions and affective challenges that academics might experience in their journey of becoming within neoliberal higher education contexts transnationally. These are examined in entanglement with intricate social, ideological, political and racial factors across different stages of academic careers.
Mahtab Janfada, Angel M. Y. Lin, Fei Victor Lim, Jiajia Eve Liu   +3 more
wiley   +1 more source

Fast radio bursts and the radio perspective on multi-messenger gravitational lensing. [PDF]

Philos Trans A Math Phys Eng Sci
Pastor-Marazuela I.
europepmc   +1 more source

Nuclear Bar, Star Formation, and Gas Fueling in the Active Galaxy NGC 4303 [PDF]

, 2000
L. Colina, Keiichi Wada
openalex   +1 more source