Results 41 to 50 of about 4,175 (247)
For most patients with chronic, progressive illnesses, maintaining good quality of life (QoL), with preserved functional capacity, is just as crucial as prolonging survival. Patients with heart failure (HF) experience much worse QoL and effort intolerance than both the general population and people with other chronic conditions, since they present a ...
Maurizio Volterrani+21 more
wiley +1 more source
Hydrogen peroxide ‐ responsive aminoferrocene prodrugs
Aminoferrocene (AF)‐based prodrugs are activated in cancer cells through reactions with H₂O₂ and other reactive oxygen species (ROS), generating electron‐rich AF’s. These, in turn, induce the production of highly toxic O2·‐ and HO·, leading to cancer cell death.
Marlies Körber+3 more
wiley +1 more source
What's New? Our research highlights how tumor sialylation affects tumor growth and reshapes the immune tumor microenvironment in colorectal cancer. We demonstrate for the first time that complete removal of sialic acids from colorectal tumor cells elicits a robust anti‐tumor immune response, but does not enhance anti‐PD‐L1 blockade efficacy.
Irene van der Haar Àvila+11 more
wiley +1 more source
Gut microbiota and tuberculosis
This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.
Yanhua Liu+39 more
wiley +1 more source
Radio Properties of Active Nearby Spiral Galaxies [PDF]
A. G. de Bruyn
openalex +1 more source
ATAC‐seq in Emerging Model Organisms: Challenges and Strategies
Principle of ATAC‐seq (left), overview of arthropod species with published ATAC‐seq data (middle), summary of experimental design (right). ABSTRACT The Assay for Transposase‐Accessible Chromatin with sequencing (ATAC‐seq) is a versatile and widely utilized method for identifying potential regulatory regions, such as promoters and enhancers, within a ...
Duğçar Ebrar Erdoğan+13 more
wiley +1 more source
The Nature of Quasars and the Active Nuclei of Galaxies [PDF]
Виталий Л. Гинзбург+1 more
openalex +1 more source
Nuclear Activity in Nearby Galaxies [PDF]
A significant fraction of nearby galaxies show evidence of weak nuclear activity unrelated to normal stellar processes. Recent high-resolution, multiwavelength observations indicate that the bulk of this activity derives from black hole accretion with a wide range of accretion rates.
openaire +3 more sources
Highly selective oxidation of thiazolidin‐4‐ones to sulfoxides and sulfones with Oxone and KMnO4, respectively. ABSTRACT S‐Oxidation of 3‐Aryl‐2‐trichloromethyl‐1,3‐thiazolidin‐4‐ones with Oxone was investigated. For all compounds evaluated, selective oxidation to the sulfoxide versus the sulfone was realized using 3 equivalents of Oxone at room ...
Ahmed Y. Nuriye+3 more
wiley +1 more source
The Nature of the Energy Source in Radio Galaxies and Active Galactic Nuclei [PDF]
F. Pacini, M. Salvati
openalex +1 more source