Results 61 to 70 of about 147 (144)
Profiles of Anxiety in Children Undergoing Elective Surgery: Predictors and Perioperative Outcomes
ABSTRACT Surgery is an anxiety‐provoking event, but there are individual differences in the magnitude of experienced anxiety. The objective of this study was to identify patterns of children's preoperative anxiety, its predictors, and perioperative outcomes. The sample included 171 children (Mage = 9.95 years) undergoing elective surgery.
Kristie L. Poole +5 more
wiley +1 more source
Variation in Bird Gut Microbiota Across Dietary Guilds and Migratory Strategies
This study analyzed the gut microbiota of birds from different ecological types in Nanning, Guangxi, and found that different dietary habits (omnivory, carnivory, and herbivory) and migratory strategies (migratory and resident) significantly altered the gut microbiota of birds, but migration did not increase the inter‐individual variability of gut ...
Wenjing Zhou +7 more
wiley +1 more source
Unveiling the Functional Role of KIF21B in Microglia Inflammatory Response
Microglia express KIF21B in both sexes. KIF21B binds to microglia cytoskeleton; inflammation alters such interaction promoting a phagocytic state in females. In male microglia KIF21B modulates migration. ABSTRACT Microglia are brain immune cells that maintain homeostasis and respond to injury, changing cell morphology to drive inflammation, migration ...
Danny Ganchala +6 more
wiley +1 more source
Basal‐like breast cancer (BLBC) is aggressive and often exhibits inherent or acquired resistance to radiotherapy (RT), a primary treatment option. RT resistance is underpinned by molecular alterations, many of which are poorly understood. Here, RT‐induced transcriptomic changes were analyzed using bulk and spatial sequencing in a BLBC mouse model and ...
Garyfallia Pantelaiou‐Prokaki +12 more
wiley +1 more source
Ragomics‐Meta: An open‐source, scalable, reproducible, and extensible multi‐omics analysis workflow
Ragomics‐Meta is an open‐source, scalable, and reproducible multi‐omics workflow for metabolism‐centered analysis (https://www.raganetwork.com/). It integrates scRNA/snRNA‐seq, spatial transcriptomics, scATAC‐seq, and metabolomics modules to support quality control, dimensionality reduction, clustering, differential expression and accessibility ...
Zeping Gui +11 more
wiley +1 more source
ABSTRACT Critical bone defects present significant clinical challenges due to their debilitating nature and associated costs. Tissue engineering offers a promising solution, employing biomaterials like porous chitosan (CH) and xanthan gum (XG) membranes as scaffolds for tissue regeneration.
Julia Eduarda Schneider Gregório +7 more
wiley +1 more source
The up‐to‐date clinical progress of immune checkpoint inhibitor (ICI) therapy in solid tumors, specifically the combinational regimens between ICIs and other treatment strategies, the mechanisms underlying primary and acquired resistance, and mechanism‐matched strategies to improve clinical outcomes are synthesized in this review.
Qiongyu Zhang, Zhi Qin, Caijuan Guo
wiley +1 more source
A Context‐Aware Decision Support Framework for Scientific Experiment Configuration
ABSTRACT Introduction Defining an experimental configuration is a complex decision problem for early‐stage researchers, who must map goals, constraints, and requirements onto datasets, algorithms, and parameter settings that directly affect experimental outcomes.
Pouriya Miri +3 more
wiley +1 more source
Metagenomics revealed distinct anthropogenic signatures in the microbiome of freshwater sources on Marambaia Island, supported by the Anthropogenic Impact Index (AII). Impacted sites showed lower microbial diversity, enrichment of fecal‐associated taxa, and 14 antimicrobial resistance genes, whereas conductivity, salinity, and turbidity explained 88.1%
Bruna Barbosa de Paula +6 more
wiley +1 more source

