Results 61 to 70 of about 169 (163)

Inhibition of Ornithine Decarboxylase 1 Mitigates Denervation‐Induced Muscle Atrophy by Suppressing Proteolysis and Preserving Muscle Stem Cell Homeostasis

Cell Proliferation, EarlyView.
Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang, Feifan Chang, Siliang Ge, Fuming Cao, Pincong Fu, Haobo Zhang, Ming Chen, Yi Li, Peifu Tang, Pengbin Yin   +9 more
wiley   +1 more source

Strength‐Based Parenting and Relationship Quality in Latine Families Facing Justice System Risk

Family Relations, EarlyView.
ABSTRACT Objective To examine whether parenting practices that are shaped by culturally embedded value systems (responsiveness, autonomy granting, and affective warmth) and familism are associated with parent–adolescent relationship quality among Latine youth, and whether these associations differ by youth justice involvement and gender.
Caitlin Cavanagh, Natasha Chlebuch, April Gile Thomas   +2 more
wiley   +1 more source

Modular training resources for bioimage analysis

Journal of Microscopy, EarlyView.
Abstract Modern microscopy enables us to measure structural and dynamical properties of many biological processes and is therefore an indispensable research tool. However, the amount and complexity of the produced imaging data is steadily increasing.
Christian Tischer, Antonio Zaccaria Politi, Tim‐Oliver Buchholz, Elnaz Fazeli, Nicola Gritti, Aliaksandr Halavatyi, Sebastián González‐Tirado, Julian Hennies, Toby Hodges, Arif Khan, Dominik Kutra, Stefania Marcotti, Bugra Oezdemir, Felix Schneider, Martin Schorb, Anniek Stokkermans, Yi Sun, Nima Vakili   +17 more
wiley   +1 more source

GloBIAS survey results – An insight into the global bioimage analysis community

Journal of Microscopy, EarlyView.
Abstract There is a global need for bioimage analysis (BIA) as advances in life sciences increasingly rely on cutting‐edge imaging systems that have dramatically expanded the complexity and dimensionality of biological images. Turning these data into scientific discoveries requires scientists with effective data management skills and knowledge of state‐
Laura R. de la Ballina, Christa G. Walther, Nicholas D. Condon, Alessandro A. Felder, Martin Schätz, Bettina Schmerl, Ko Sugawara, Clara Prats, Anna Klemm, Kota Miura, Paula Sampaio, Christian Tischer, Shuichi Onami, Rocco D'Antuono, Beth A Cimini, Robert Haase, Agustin A. Corbat, Florian Levet   +17 more
wiley   +1 more source

Bioimage management and analysis in Galaxy: Tools, workflows, training, and community practices

Journal of Microscopy, EarlyView.
ABSTRACT Image analysis in the life sciences is constrained by fragmented software ecosystems, heterogeneous data formats, and limited reproducibility. These barriers hinder the reuse of image analysis methods and the sustainability of tools. In this article, we describe how the Galaxy platform enables FAIR (Findable, Accessible, Interoperable, and ...
Leonid Kostrykin, Riccardo Massei, Diana Chiang, Thomas Wollmann, Jean‐Marie Burel, David Lopez Tabernero, Yi Sun, Qi Gao, Maarten W. Paul, Pavankumar Videm, Cameron Watson, Daniel Franco‐Barranco, Anup Kumar, Nadia Goué, Reyhaneh Tavakoli Koopaei, Vladimír Ulman, Khaled Jum'ah, Krzysztof Poterlowicz, Martin Etzrodt, Arrate Muñoz‐Barrutia, Sylvia E. Le Dévédec, Josh Moore, Jeremy Goecks, Bjoern Gruening, Karl Rohr, Beatriz Serrano‐Solano   +25 more
wiley   +1 more source

Photochemical effects of Mars‐like UV irradiation on carboxylic acids in carbonaceous chondrites and expectations for abiotic background organics on Mars

Meteoritics &Planetary Science, EarlyView.
Abstract In the search for life on Mars, understanding the origin of preserved organics is critical. Expected sources include exogenous delivery, endogenous synthesis, and potentially life. Environmental processing by ultraviolet (UV) irradiation can alter these organics, obscuring hallmarks of their origin. To deconvolve these effects, we conducted an
D. K. Buckner, J. C. Aponte, A. C. Schuerger, D. I. Foustoukos, F. Seguin, M. B. Wilhelm, G. Cooper, A. J. Williams   +7 more
wiley   +1 more source

Post‐flight assessment of the OSIRIS‐REx Sample Return Capsule (SRC) for organic and other potential contaminants

Meteoritics &Planetary Science, EarlyView.
Abstract Regolith samples from the carbonaceous asteroid Bennu were stowed and delivered to Earth in the OSIRIS‐REx spacecraft's Sample Return Capsule (SRC). We applied multiple analytical techniques to study the components of the post‐flight SRC, with a focus on assessing the conditions and any contaminants to which the Bennu samples were exposed ...
Scott A. Sandford, Jason P. Dworkin, Kevin Righter, Feargus A. J. Abernethy, Romain Alosius, José C. Aponte, James Ball, Eve L. Berger, Denise K. Buckner, Henner Busemann, Simon J. Clemett, George Cody, Jamie Elsila, Dionysis I. Foustoukos, Ian A. Franchi, Daniel P. Glavin, Monica M. Grady, Heather V. Graham, Philipp R. Heck, Amy E. Hofmann, Yongsong Huang, Bumsoo Kim, Daniela Krietsch, Nicole G. Lunning, Colin Maden, Hannah L. McLain, Angel Mojarro, Michel Nuevo, Philippe Schmitt‐Kopplin, Ewerton Santos, Maria Schönbächler, Christopher J. Snead, Kathie L. Thomas‐Keprta, Alexander B. Verchovsky, Harold C. Connolly Jr., Dante S. Lauretta   +35 more
wiley   +1 more source

Regulation by the Transcriptional Regulator YdcI in E. coli and (p)ppGpp‐Dependent Activation of ydcI Expression

Molecular Microbiology, EarlyView.
YdcI, a LysR‐type transcription regulator in Escherichia coli, regulates loci like iraP and mqo. Its expression is induced by (p)ppGpp under stress conditions, and protein levels rise during mid‐exponential growth, connecting its role to stress response and metabolism control. ABSTRACT YdcI, a LysR‐type transcription regulator, has been associated with
Ria Basu Roy, Karin Schnetz
wiley   +1 more source

Nature's Complexity Alive: Farewell to Several Unificatory Cosmological Arguments for Monism

Noûs, EarlyView.
ABSTRACT Throughout history, numerous thinkers have claimed that monism—in the form of priority monism, existence monism, monotheistic monism, or versions that posit an extra‐cosmic ultimate being—theoretically surpasses pluralism, above all by positing a unified universe.
Lok‐Chi Chan
wiley   +1 more source

A C‐repeat binding factor–salicylic acid (CBF–SA) module links wound‐induced evaporative cooling to tissue repair in plants

New Phytologist, EarlyView.
A model of the C‐repeat binding factor–salicylic acid (CBF–SA) module in plant wound healing. Summary Repairing damaged tissues is essential for the survival of all organisms. In plants, tissue injury rapidly triggers defense and repair programs. However, the molecular mechanisms linking early injury cues to the later stage of wound repair remain ...
Joseph Michael Balem, Chenjiao Tan, Nathália Cássia Ferreira Dias, Mariah Arnold, Sorrel Tran, Paul M. Severns, Paulo José Pereira Lima Teixeira, Changying Li, Li Yang   +8 more
wiley   +1 more source