Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres +21 more
wiley +1 more source
Modelling the chemical evolution of the Galaxy halo [PDF]
We study the chemical evolution and formation of the Galactic halo through the analysis of its stellar metallicity distribution function and some key elemental abundance patterns.
Brusadin, G., Matteucci, F., Romano, D.
core +2 more sources
A grid of chemical evolution models along the Hubble Sequence [PDF]
We have computed a grid of multiphase chemical evolution models whose results are valid for any spiral galaxy, using as input the maximum rotation velocity and the morphological type or index T.Comment: 2 pag., contribution to the conference Cosmic ...
Diaz, Angeles I. +2 more
core +3 more sources
The Origin of the Nuclear Star-forming Ring in NGC 3182
We investigate the stellar and ionized gas kinematics, and stellar populations of NGC 3182 galaxy using integral field spectrograph data from the Calar Alto Legacy Integral Field Area survey. We try to clarify the nature of the ring structure in NGC 3182.
Mina Pak +3 more
doaj +1 more source
Effects of thermohaline instability and rotation-induced mixing on the evolution of light elements in the Galaxy : D, 3He and 4He [PDF]
Recent studies of low- and intermediate-mass stars show that the evolution of the chemical elements in these stars is very different from that proposed by standard stellar models.
Asplund +88 more
core +3 more sources
He abundances in disc galaxies. I. Predictions from cosmological chemodynamical simulations [PDF]
Accepted for publication in A&AWe investigate how the stellar and gas-phase He abundances evolve as a function of time within simulated star-forming disc galaxies with different star formation histories.
Kobayashi, Chiaki +4 more
core +5 more sources
A 30m Large Program: The CO Line Atlas of the Whirlpool Galaxy Survey (CLAWS) [PDF]
Robust knowledge of the distribution, amount, and physical/chemical state of the cold molecular (H2) gas is key to understanding galaxy evolution. With the help of multi-CO line observations, it is possible to study the molecular gas distribution and ...
den Brok Jakob, Bigiel Frank
doaj +1 more source
Chemical evolution of local galaxies
We show the results of a study using the spectral synthesis technique study to measure the chemical evolution of local galaxies. The main parameters measured are the chemical enrichment history (ChEH) and the evolution of the stellar mass-metallicity relation (MZR) over cosmic time.
Fariña, Artemi Camps +2 more
openaire +1 more source
The Chemical Evolution of the Galaxy [PDF]
Over the last few years, our picture of the chemical evolution of the Galaxy has changed substantially. These changes are of interest because chemical evolution provides a common point of contact for most astrophysical processes of importance to galaxy evolution.
openaire +1 more source
Stellar populations in gas-rich galaxy mergers I. Dependence on star formation history
We investigate the nature of stellar populations of major galaxy mergers between late-type spirals considerably abundant in interstellar medium by performing numerical simulations designed to solve both the dynamical and chemical evolution in a self ...
Bekki, Kenji, Shioya, Yasuhiro
core +1 more source

