Results 101 to 110 of about 102,930 (210)
BAF60/SWP73 subunits define subclasses of SWI/SNF chromatin remodelling complexes in Arabidopsis
Summary Evolutionarily conserved switch‐defective/sucrose nonfermentable (SWI/SNF) ATP‐dependent chromatin remodelling complexes (CRCs) alter nucleosome positioning and chromatin states, affecting gene expression to regulate important processes such as proper development and hormonal signalling pathways.
Sebastian P. Sacharowski+23 more
wiley +1 more source
Engineering Gypsophila elegans hairy root cultures to produce endosomal escape‐enhancing saponins
Summary The limited cytosolic delivery of DNA and protein‐based therapeutics due to endosomal entrapment reduces drug efficacy, increasing treatment costs and possible side effects in human and veterinary medicine as a consequence of higher administered dosages.
Elia Lacchini+4 more
wiley +1 more source
ABSTRACT This article examines a silence in the histories of the formation of peace and conflict studies as an academic field, focusing on the elision of a female‐identified academic: Gladdys Esther Muir. Muir occasionally appears in histories as a datapoint in peace education chronologies where she is listed as the director of the first peace studies ...
Reina C. Neufeldt
wiley +1 more source
Lessons from the void: What Boltzmann brains teach
Abstract Some physical theories predict that almost all brains in the universe are Boltzmann brains, that is, short‐lived disembodied brains that are accidentally assembled as a result of thermodynamic or quantum fluctuations. Physicists and philosophers of physics widely regard this proliferation as unacceptable, and so take its prediction as a basis ...
Bradford Saad
wiley +1 more source
Visionaries and Crackpots, Maniacs and Saints: Existential Risk and the Politics of Longtermism
ABSTRACT Despite advancing strong claims about our collective priorities, longtermism has received little attention in debates in political philosophy. I first provide an account of longtermism that highlights the way it departs from established work on intergenerational justice.
Alex McLaughlin
wiley +1 more source
ABSTRACT Companies increasingly adopt internal norms to enhance compliance with legal rules. However, the rapid growth in volume and complexity of such internal rules may obstruct employee knowledge and understanding of such internal rules, and therefore also their compliance.
Nils Köbis+4 more
wiley +1 more source
Caxton's Afterlife in Manuscript (c.1475‐c.1500)
Abstract At least thirty‐five manuscript copies of Caxton's prints have been found so far. This article explores the implications of such manuscript copies of Caxton's prints and, interrupting the linear history of the book, considers Caxton's appeal beyond print in manuscript.
Aditi Nafde
wiley +1 more source
Abstract Space exploration involves many dangers including galactic cosmic radiation (GCR). This class of radiation includes high‐energy protons and heavy ionizing ions. NASA has defined GCR as a carcinogenic risk for long‐duration space missions. To date, no clear strategy has been developed to counter chronic GCR exposure.
Siena Edwards+3 more
wiley +1 more source
Women in space: A review of known physiological adaptations and health perspectives
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford+4 more
wiley +1 more source
Abstract Microgravity is associated with stature increases, back pain and post‐flight intervertebral disc (IVD) herniation. This study aims to determine whether 30 s seated 50% body weight (BW) axial loading is comparable to 15 min sitting upright in 1 g upon changes in stature, anterior lumbar IVD height (via ultrasound), passive vertebral stiffness ...
David Marcos‐Lorenzo+6 more
wiley +1 more source