Results 81 to 90 of about 12,566,242 (368)

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Galaxy Groups as the Ultimate Probe of AGN Feedback

Galaxies
The co-evolution between supermassive black holes and their environment is most directly traced by the hot atmospheres of dark matter halos. The cooling of the hot atmosphere supplies the central regions with fresh gas, igniting active galactic nuclei ...
Dominique Eckert, Fabio Gastaldello, Ewan O’Sullivan, Alexis Finoguenov, Marisa Brienza, the X-GAP Collaboration   +5 more
doaj   +1 more source

The Metal Content of the Hot Atmospheres of Galaxy Groups

Universe, 2021
Galaxy groups host the majority of matter and more than half of all the galaxies in the Universe. Their hot (107 K), X-ray emitting intra-group medium (IGrM) reveals emission lines typical of many elements synthesized by stars and supernovae.
Fabio Gastaldello, Aurora Simionescu, Francois Mernier, Veronica Biffi, Massimo Gaspari, Kosuke Sato, Kyoko Matsushita   +6 more
doaj   +1 more source

A derivation of masses and total luminosities of galaxy groups and clusters in the maxBCG catalogue [PDF]

, 2015
We report the results of a multi-waveband analysis of the masses and luminosities of $\sim$600 galaxy groups and clusters identified in the maxBCG catalogue.
R. Proctor, C. M. D. Oliveira, L. Azanha, R. Dupke, R. Overzier   +4 more
semanticscholar   +1 more source

Scintillation Response of 0D Cs3Cu2I5 Thin Layers to Light‐ and Heavy‐Ion Irradiation

Advanced Photonics Research, EarlyView.
Driven by increasing interest in uncovering the remarkable photoluminescence quantum yield of Cs3Cu2I5, polycrystalline thin layers are synthesized to investigate its radioluminescence response to energetic ions. Its spectroscopic capability is assessed in a wide range of ion mass and internal excitation processes are explored.
Mátyás Hunyadi, Attila Csík, Cintia Hajdu, Csaba Janáky, István Rajta, Gergely F. Samu, Lóránt Csige   +6 more
wiley   +1 more source

Core to Cosmic Edge: SIMBA-C’s New Take on Abundance Profiles in the Intragroup Medium at z = 0

Universe
We employ the simba-c cosmological simulation to study the impact of its upgraded chemical enrichment model (Chem5) on the distribution of metals in the intragroup medium (IGrM).
Aviv Padawer-Blatt, Zhiwei Shao, Renier T. Hough, Douglas Rennehan, Ruxin Barré, Vida Saeedzadeh, Arif Babul, Romeel Davé, Chiaki Kobayashi, Weiguang Cui, François Mernier, Ghassem Gozaliasl   +11 more
doaj   +1 more source

Galaxy And Mass Assembly (GAMA): the halo mass of galaxy groups from maximum-likelihood weak lensing [PDF]

, 2014
We present a maximum-likelihood weak-lensing analysis of the mass distribution in optically selected spectroscopic Galaxy Groups (G3Cv5) in the Galaxy And Mass Assembly (GAMA) survey, using background Sloan Digital Sky Survey (SDSS) photometric galaxies.
Jiaxin Han, V. Eke, C. Frenk, R. Mandelbaum, P. Norberg, M. Schneider, J. Peacock, Y. Jing, I. Baldry, J. Bland-Hawthorn, S. Brough, Michael J. I. Brown, J. Liske, J. Loveday, A. Robotham   +14 more
semanticscholar   +1 more source

Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial

Advanced Science, EarlyView.
In people with overweight or obesity, regular exercise even without weight loss or vitamin D supplementation completely prevents the usual winter decline in the vitamin D metabolite that maintains health at a cellular level, 1,25(OH)2D3, and ameliorates the decline in the vitamin D status marker 25(OH)D.
Oliver J. Perkin, Sophie E. Davies, Martin Hewison, Kerry S. Jones, Javier T. Gonzalez, James A. Betts, Carl Jenkinson, Mark A. Lindsay, Sarah R. Meadows, Damon A. Parkington, Albert Koulman, Dylan Thompson   +11 more
wiley   +1 more source

No Evidence of Asymmetrically Enhanced Star Formation in Infalling Galaxies in UNIONS

The Astrophysical Journal
Ram pressure stripping is a well-known environmental quenching mechanism that removes gas from galaxies infalling into groups and clusters. In some extreme examples of ram pressure stripping, galaxies with extended gas tails show evidence of enhanced ...
Lauren M. Foster, Laura C. Parker, Stephen Gwyn, Ian D. Roberts, James E. Taylor, Michael J. Hudson, Alan W. McConnachie, Thomas de Boer   +7 more
doaj   +1 more source