Results 41 to 50 of about 53,384 (285)

Interaction of the oncofetal Thomsen-Friedenreich antigen with galectins in cancer progression and metastasis

open access: yesFrontiers in Oncology, 2016
Aberrant glycosylation of cell membrane proteins is a universal feature of cancer cells. One of the most common glycosylation changes in epithelial cancer is the increased occurrence of the oncofetal Thomsen-Friedenreich disaccharide Galβ1-3GalNAc (T or ...
Paulina eSindrewicz   +2 more
doaj   +1 more source

Teladorsagia Circumcincta Galectin-Mucosal Interactome in Sheep

open access: yesVeterinary Sciences, 2021
Teladorsagia circumcincta is the most important gastrointestinal parasite in the livestock industry in temperate regions around the world, causing great economic losses.
Nur Nasuha Hafidi   +7 more
doaj   +1 more source

Galectin-8 and galectin-9 are novel substrates for thrombin [PDF]

open access: yesGlycobiology, 2006
Galectin-8 and galectin-9, which each consist of two carbohydrate recognition domains (CRDs) joined by a linker peptide, belong to the tandem-repeat-type subclass of the galectin family. Alternative splicing leads to the formation of at least two and three distinct splice variants (isoforms) of galectin-8 and galectin-9, respectively, with tandem ...
Nozomu, Nishi   +4 more
openaire   +2 more sources

The role of Galectin-3 and Survivin in invasion and drug resistance in human cancer [PDF]

open access: yes, 2003
Galectin-3 is an apoptosis-related gene previously found to be over-expressed in invasive tumours and to cause in v itroinvasiveness and metastasis in colon, breast and thyroid follicular cancer cells.
Linehan, Rasha
core   +2 more sources

Galectin-1 and galectin-3 as modulators of systemic CD4+ T-lymphocyte balance in colorectal cancer

open access: yesБюллетень сибирской медицины
Aim. To evaluate the relationships between plasma levels of galectin-1 and galectin-3 and the composition of CD4+ T-lymphocyte subpopulations (Th1, Th17, and Treg) in patients with colorectal cancer (CRC) and to determine a direct in vitro modulatory ...
V. S. Poletika   +4 more
doaj   +1 more source

Effect of galectin-3 in the pathogenesis of arteriovenous fistula stenosis formation

open access: yesRenal Failure, 2021
Objective This study sought to investigate the effect of local expression of galectin-3 in the development of stenotic arteriovenous fistula (AVF). Methods We collected stenotic venous tissues, adjacent nonstenotic venous tissues, and blood samples from ...
Lin Ruan   +6 more
doaj   +1 more source

The expression profiles of the galectin gene family in primary and metastatic papillary thyroid carcinoma with particular emphasis on galectin-1 and galectin-3 expression [PDF]

open access: yes, 2014
Introduction Galectin family members have been demonstrated to be abnormally expressed in cancer at the protein and mRNA level. This study investigated the levels of galectin proteins and mRNA expression in a large cohort of patients with papillary ...
Sullivan, Emily   +9 more
core   +1 more source

Placental Expression Patterns of Galectin-1, Galectin-2, Galectin-3 and Galectin-13 in Cases of Intrauterine Growth Restriction (IUGR) [PDF]

open access: yesInternational Journal of Molecular Sciences, 2016
Galectins (gal) are members of the mammalian β-galactoside-binding proteins and recognize Galβ1-4GlcNAc and Galβ1-4GalNac (Thomsen-Friedenreich antigen (TF)) sequences of several cell surface oligosaccharides. In this study, gal-1, -2, -3 and -13 were investigated systematically in the trophoblast and decidua compartment of intrauterine growth ...
Stefan Hutter   +7 more
openaire   +3 more sources

The Clinical Utility of Biochemical Biomarkers in Colorectal Cancer [PDF]

open access: yesMiddle East Journal of Cancer
Colorectal cancer (CRC) ranks as the third most prevalent cancer worldwide and is a leading cause of cancer-related mortality. Since many colon cancers present no significant clinical symptoms, identifying new biomarkers or a set of biological indicators
Durdi Qujeq   +5 more
doaj   +1 more source

Inhibition of LPS-Induced Inflammatory Response of Oral Mesenchymal Stem Cells in the Presence of Galectin-3

open access: yesBiomedicines, 2023
Galectin-3 (GAL-3) is a beta-galactoside binding lectin produced by mesenchymal stem cells (MSCs) and other cell sources under inflammatory conditions. Several studies have reported that GAL-3 exerts an anti-inflammatory action, regulated by its natural ...
Alessia Paganelli   +6 more
doaj   +1 more source

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