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Differential Cellular Expression of Galectin-1 and Galectin-3 After Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is a devastating sub-type of stroke with no proven treatment. Given the emerging role of Galectin-1 and Galectin-3 in neuroimmune responses, the objective of the current manuscript is to elucidate hemorrhagic-injury induced
Frederick Bonsack +1 more
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N-glycosylation of membrane receptors is important for a wide variety of cellular processes. In the immune system, loss or alteration of receptor glycosylation can affect pathogen recognition, cell-cell interaction, and activation as well as migration ...
Paola de Haas +4 more
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Effects of Apocynin against Monosodium Glutamate-Induced Oxidative Damage in Rat Kidney
Objective: Monosodium glutamate causes oxidative stress that affects a variety of organ systems, along with the kidney. The aim of this study was to evaluate the protective role of apocynin in kidney degeneration caused by monosodium glutamate using ...
Merve Açıkel Elmas +4 more
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A Synthetic Galectin Mimic [PDF]
AbstractGalectins are a galactoside specific subclass of carbohydrate binding proteins (lectins) involved in various cellular activities, certain cancers, infections, inflammations, and many other biological processes. The molecular basis for the selectivity of galectins is well‐documented and revolves around appropriate interaction complementarity: an
Brian J. J. Timmer +3 more
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Intrinsic tryptophan fluorescence spectroscopy reliably determines galectin-ligand interactions
Galectins are involved in the regulation of divergent physiological and pathological processes and are increasingly recognized to play important roles in a number of diseases.
Paulina Sindrewicz +5 more
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Possible important roles of galectins in the healing of human fetal membranes
The fetal membranes healing is a complex and dynamic process of replacing devitalized and missing cellular structures and tissue layers. Multiple cells and extracellular matrices, and cell differentiation, migration and proliferation may participate in ...
Jia-Le Chen +6 more
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Both vertebrates and invertebrates display active innate immune mechanisms for defense against microbial infection, including diversified repertoires of soluble and cell-associated lectins that can effect recognition and binding to potential pathogens ...
Gerardo R. Vasta +16 more
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Galectins are a family of proteins with an affinity for β-galactosides that have roles in neuroprotection and neuroinflammation. Several studies indicate that patients with neurodegenerative diseases have alterations in the concentration of galectins in ...
Edgar Ramos-Martínez +8 more
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Galectins are a family of animal lectins with an affinity for beta-galactosides. They are differentially expressed by various tissues and appear to be functionally multivalent, exerting a wide range of biological activities both during development and in adult tissue.
Saussez, Sven, Kiss, Robert
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Coding of biological information is not confined to nucleic acids and proteins. Endowed with the highest level of structural versatility among biomolecules, the glycan chains of cellular glycoconjugates are well-suited to generate molecular messages ...
Paul V. Murphy +2 more
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