Results 21 to 30 of about 51,657 (292)
Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation. [PDF]
, 2015 Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory diseases. Although the role of toll-like receptor 4 (TLR4) in microglia's inflammatory response is fully acknowledged, little is ...
Martina Svensson +81 more
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Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. [PDF]
, 2012 The S-type lectin galectin-9 binds to the negative regulatory molecule Tim-3 on T cells and induces their apoptotic deletion or functional inactivation.
Cheng, Y +59 more
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Effects of Apocynin against Monosodium Glutamate-Induced Oxidative Damage in Rat Kidney
European Journal of Biology, 2022 Objective: Monosodium glutamate causes oxidative stress that affects a variety of organ systems, along with the kidney. The aim of this study was to evaluate the protective role of apocynin in kidney degeneration caused by monosodium glutamate using ...
Merve Açıkel Elmas +4 more
doaj +1 more source
Differential Cellular Expression of Galectin-1 and Galectin-3 After Intracerebral Hemorrhage
Frontiers in Cellular Neuroscience, 2019 Intracerebral hemorrhage (ICH) is a devastating sub-type of stroke with no proven treatment. Given the emerging role of Galectin-1 and Galectin-3 in neuroimmune responses, the objective of the current manuscript is to elucidate hemorrhagic-injury induced
Frederick Bonsack +1 more
doaj +1 more source
Possible important roles of galectins in the healing of human fetal membranes
Frontiers in Endocrinology, 2022 The fetal membranes healing is a complex and dynamic process of replacing devitalized and missing cellular structures and tissue layers. Multiple cells and extracellular matrices, and cell differentiation, migration and proliferation may participate in ...
Jia-Le Chen +6 more
doaj +1 more source
Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer [PDF]
, 2005 Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins and their binding sites using labeled tissue lectins as well as the binding profile of hyaluronic acid as an approach to define new prognostic markers.
Szöke, Tamas +9 more
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Plasma Galectin-9 Concentrations in Normal and Diseased Condition
Cellular Physiology and Biochemistry, 2018 Background/Aims: Galectin-9 is a soluble immune modulator with versatile functions, including a role as an immune checkpoint molecule. Therefore, the amount of galectin-9 in the blood may reflect an individual’s immunological balance.
Toshiro Niki +6 more
doaj +1 more source
Frontiers in Chemistry, 2020 N-glycosylation of membrane receptors is important for a wide variety of cellular processes. In the immune system, loss or alteration of receptor glycosylation can affect pathogen recognition, cell-cell interaction, and activation as well as migration ...
Paola de Haas +4 more
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Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin [PDF]
, 2002 The squamous stratified epithelia contain a proliferative (harboring mitotic activity) and a differentiating compartment. Due to the potential of protein-carbohyd rate interactions to regulate cellular activities we introduced a mammalian lectin to cyto-
Holíkova, Zuzana +7 more
core +1 more source
Biomolecules, 2022 Galectins are a family of proteins with an affinity for β-galactosides that have roles in neuroprotection and neuroinflammation. Several studies indicate that patients with neurodegenerative diseases have alterations in the concentration of galectins in ...
Edgar Ramos-Martínez +8 more
doaj +1 more source