Results 11 to 20 of about 36,931 (245)
Galectinology of Equine Pregnancy
Galectins are a family of proteins that bind to glycans, acting in a cytokine-like manner throughout the body. In the majority of mammalians, galectins have been found to be involved in pregnancy maintenance, but few studies have evaluated this in the ...
Carleigh E. Fedorka +2 more
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Galectins in the Tumor Microenvironment: Focus on Galectin-1 [PDF]
In the last decades, the focus of cancer research has moved from epithelial cells to the tumor milieu, in an effort to better understand tumor development and progression, and with the important end goal of translating this knowledge into effective therapies.
Martínez-Bosch, Neus +1 more
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Galectins can serve as biomarkers in COVID-19: A comprehensive systematic review and meta-analysis
BackgroundGalectins are an eleven-member class of lectins in humans that function as immune response mediators and aberrancies in their expression are commonly associated with immunological diseases.
Amir Hossein Behnoush +7 more
doaj +1 more source
“Repair Me if You Can”: Membrane Damage, Response, and Control from the Viral Perspective
Cells are constantly challenged by pathogens (bacteria, virus, and fungi), and protein aggregates or chemicals, which can provoke membrane damage at the plasma membrane or within the endo-lysosomal compartments.
Coralie F. Daussy, Harald Wodrich
doaj +1 more source
We previously observed that genomic loss of galectin‐3 (Gal‐3; encoded by Lgals3) in mice has a significant protective effect on age‐related bone loss.
Kevin A. Maupin +5 more
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Galectin-1 and Galectin-3 in Chronic Pancreatitis [PDF]
Galectin-1 and galectin-3 have important functions in cell-cell interactions, cell adhesion to extracellular matrix, the organization of extracellular matrix, and tissue remodeling. To assess their potential role in chronic pancreatitis (CP), we examined their expression by Northern blot analysis, in situ hybridization, immunohistochemistry, and ...
Wang L +7 more
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Atg8ylation as a general membrane stress and remodeling response
The yeast Atg8 protein and its paralogs in mammals, mammalian Atg8s (mAtg8s), have been primarily appreciated for their participation in autophagy. However, lipidated mAtg8s, including the most frequently used autophagosomal membrane marker LC3B, are ...
Suresh Kumar, Jingyue Jia1, Vojo Deretic
doaj +1 more source
Tumor Microenvironment-Associated Extracellular Matrix Components Regulate NK Cell Function
The tumor microenvironment (TME) is composed of multiple infiltrating host cells (e.g., endothelial cells, fibroblasts, lymphocytes, and myeloid cells), extracellular matrix, and various secreted or cell membrane-presented molecules.
Gustavo Rodrigues Rossi +2 more
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The role of salivary galectin-3 and galectin-9 levels in plaque-induced gingivitis and periodontitis
Background: This study aimed to compare the salivary galectin-3 and galectin-9 levels in periodontitis, gingivitis, and periodontally healthy patients. Methods: This study included 75 non-smokers who were systemically healthy.
Zerrin Barut +6 more
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Plasma Galectin-9 Concentrations in Normal and Diseased Condition
Background/Aims: Galectin-9 is a soluble immune modulator with versatile functions, including a role as an immune checkpoint molecule. Therefore, the amount of galectin-9 in the blood may reflect an individual’s immunological balance.
Toshiro Niki +6 more
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