Results 111 to 120 of about 92,008 (245)
Obesity, EarlyView.ABSTRACT Objective This study compared the efficacy of metabolic/bariatric surgery (MBS) and GLP‐1 receptor agonists (GLP‐1 RAs), including dual GLP‐1/GIP analogues, for weight and metabolic outcomes in adults with obesity. Methods A network meta‐analysis of randomized controlled trials compared MBS or GLP‐1 RAs versus lifestyle intervention in adults ...
Lucas Sabatella +9 more
wiley +1 more source
Obesity, EarlyView.ABSTRACT Objective Cholecystectomy (GBX) may alter energy metabolism, but human evidence is limited. We examined whether GBX alters energy expenditure (EE), respiratory exchange ratio (RER), and substrate oxidation. Methods A total of 384 healthy Southwestern Indigenous American adults (222 males, age 28 ± 6 years) were studied, including individuals ...
Beyza N. Aydin +6 more
wiley +1 more source
Real‐World Weight Loss Is Associated With a Reduction in Cancer Risk
Obesity, EarlyView.ABSTRACT Objective Obesity is a major risk factor for multiple cancers, yet the impact of nonsurgical weight loss on cancer risk remains uncertain. Our objective was to evaluate whether real‐world nonsurgical weight loss is associated with a reduced risk of developing cancer.
Kenda Alkwatli +7 more
wiley +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Noonan syndrome (NS) is a rare multisystemic condition among the RASopathy group, characterized by a broad phenotypic spectrum and genetic variability. It results from pathogenic variants in genes regulating the RAS/MAPK pathway, affecting cell proliferation and differentiation.
Romain Martineau +10 more
wiley +1 more source
Portal Hypertension &Cirrhosis, EarlyView.CN‐TIPS is a nationwide, multicenter prospective registry that will enroll 10,000 adults with portal hypertension undergoing transjugular intrahepatic portosystemic shunt in China, integrating perioperative clinical and hemodynamic metrics with standardized imaging (including computational modeling in a dedicated subcohort) and multi‐omics biospecimens,
Yi Xiang +20 more
wiley +1 more source
Portal Hypertension &Cirrhosis, EarlyView.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has become one of the leading causes of chronic liver diseases in China and even globally. Early non‐invasive diagnosis and grading MASLD, along with timely intervention, are crucial for assessing the disease condition and slowing the disease progression.
Liyun Xue +3 more
wiley +1 more source
Phytotherapy Research, EarlyView.Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi +12 more
wiley +1 more source
Inter‐Crystal Spacing of Implantable Polymeric Surfaces as a Key Suppressor of Microbial Adhesion.
Small, EarlyView.Biofilm formation on implantable devices is addressed by controlling inter‐crystal spacing in shape memory polymers. Repeated shape recovery aligns and enlarges crystalline phases and reduces amorphous regions, enhancing bacterial repellency. Three biofilm‐forming bacteria show reduced adhesion, and a one‐year dog bile‐duct model maintains function ...
Kang Suk Lee +5 more
wiley +1 more source
World Journal of Surgery, EarlyView.Bile leakage is a severe complication after cholecystectomy and is associated with an increased risk of morbidity and mortality. The aim of this study was to evaluate the incidence of bile leakage post‐cholecystectomy and to identify potential risk factors and their association with changes in the incidence of bile leakage over time.
Layla Mirzaei +3 more
wiley +1 more source
Gallbladder mucinous cystic neoplasm: Diagnostic challenges and multimodality imaging correlation. [PDF]
Radiol Case RepAlamgir R +4 more
europepmc +1 more source