Results 131 to 140 of about 5,966 (169)
British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1845-1856, June 2026.Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen +4 more
wiley +1 more source
Cancer Innovation, Volume 5, Issue 3, June 2026.This study demonstrates multiple primary malignancies (MPMs) occur in 4.01% of gastric cancer patients and most commonly involve the esophagus, colorectum, and lung. Distinct differences are observed between synchronous and metachronous cases. These findings establish a clinical and epidemiological framework to inform future investigations into MPMs in
Guiling Zhu +6 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Background Insomnia is a common clinical symptom that significantly impairs quality of life (QOL) and it frequently occurs in cancer patients. However, the risk of insomnia in Japanese cancer patients compared with cancer‐free patients has not yet been studied.
Risa Murakami +2 more
wiley +1 more source
Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Purpose Biliary tract cancer (BTC) represents a heterogeneous disease with highly lethal malignancy and poor clinical outcomes. Here, we aimed to evaluate its genomic profiles to promote the development of precision medicine for BTC. Materials and Methods Genomic analysis of 134 BTC patients was performed by using targeted panel sequencing in ...
Xia Yang +4 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 6, June 2026.Individuals with Down syndrome have distinctive cancer profiles as compared with the general US population. Healthcare guidelines related to cancer screenings should reflect these unique profiles. ABSTRACT Introduction It is known that individuals with Down syndrome (DS) have a significantly different spectrum of malignancies and neoplasms.
Veronica Fitzpatrick +6 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 6, June 2026.Estimating Cancer Prevalence in Japan: Insights from the Osaka Cancer Registry ABSTRACT Owing to improved prognosis, cancer survivors are a growing population; however, little is known about their prevalence in Asian countries. This study estimated the prevalence and characteristics of cancer survivors in Japan, including long‐term survivors.
Haruka Kudo +7 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Aim Upper gastrointestinal bleeding (UGIB) is associated with an unfavorable outcome in cancer patients. In patients with biliary tract cancer (BTC), data on the incidence, management, and prognostic implications of UGIB are limited. This study investigated the prevalence, treatment efficacy, and prognostic factors associated with UGIB in BTC.
Jan Christoph Schumacher +8 more
wiley +1 more source
Severe Lactic Acidosis in Decompensated Cirrhosis Despite Nondiagnostic Imaging
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Lactic acidosis is a strong predictor of mortality in cirrhosis, reflecting both impaired hepatic clearance and systemic tissue hypoxia. We describe a 38‐year‐old man with decompensated alcohol‐associated cirrhosis who developed severe lactic acidosis despite stable hemodynamics and initially nondiagnostic vascular imaging.
Nakul Ganju +5 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Drug‐induced liver injury (DILI) remains a diagnosis of exclusion and requires systematic causality assessment. Meropenem is generally considered hepatically safe; however, rare cases of idiosyncratic DILI have been reported. We describe a 33‐year‐old female who developed progressive elevation of liver tests following exposure to meropenem ...
Nidal Mutawodeh +6 more
wiley +1 more source
Rising Inpatient Demands for Inherited Metabolic Disorders: Impact on Pediatric Capacity
American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1423-1426, June 2026.
Maria Paula Silva +7 more
wiley +1 more source