Results 161 to 170 of about 125,645 (313)

Self‐Reported Health Problems of Birthing Persons During the First and Second Postpartum Years: Scope and Correlates

Birth, EarlyView.
ABSTRACT Background Postpartum health‐related problems are diverse, and some may extend beyond the first postpartum year. The purpose of this study was to describe women's postpartum health problems in the first and second postpartum years. Methods We analyzed data from an online survey (N = 427) conducted in 2024.
Sudhathai Sirithepmontree, Lina Palomares, Lorraine O. Walker   +2 more
wiley   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

A case of subserosal bile infiltration due to gallbladder injury during robot-assisted nephrectomy (with video). [PDF]

J Surg Case Rep
Minezaki S, Miura F, Ueno K, Ikehata Y, Nankaku A, Yamazaki K, Takashima J, Fujimoto D, Kobayashi H, Yokoyama M, Aso T, Takahashi M, Sano K, Inoue Y, Fukagawa T.   +14 more
europepmc   +1 more source

How to Do a Laparoscopic Left Hepatectomy for Cystic Lesions Compressing the Middle Hepatic Vein: The Hemodynamic Advantage of Pneumoperitoneum

ANZ Journal of Surgery, EarlyView.
Jonathan Ben Daniel, Krishna Kotecha, Kai Brown, Anubhav Mittal, Jaswinder Samra   +4 more
wiley   +1 more source

PABPC1 in Cancer: From a Translational Housekeeper to a Stress‐Responsive Regulatory Hub

Cancer Science, EarlyView.
PABPC1 shifts from a translational housekeeper to a stress‐responsive oncogenic hub via phase separation, PTMs, and non‐coding RNA crosstalk, selectively driving oncogene translation and therapy resistance in cancer. ABSTRACT PABPC1, long recognized as a constitutive translational housekeeper, has emerged as a stress‐responsive translational ...
Cuiwei Zhang, Ye Zhu, Wenbo Long
wiley   +1 more source

Assessment of MRD and Longitudinal Monitoring of Post‐Surgery Biliary Tract Cancer With a Customized ctDNA Panel

Cancer Science, EarlyView.
A customized panel was established for BTC MRD detection. Preoperative ctDNA detection was associated with pathological stage and poorer RFS and OS. Longitudinal monitoring detected ctDNA before radiological recurrence in 72.7% of patients, with a median lead time of 77 days, supporting ctDNA as a complementary prognostic biomarker with CA19‐9 ...
Yoshihito Shinohara, Toru Nakamura, Yasutoshi Kimura, Takeshi Murakami, Shigeyuki Kojima, Toshikazu Yamaguchi, Kanako C. Hatanaka, Ryo Okazaki, Yosuke Kitayama, Keita Fukuda, Fabio Pittella‐Silva, Yusuke Nakamura, Satoshi Hirano, Siew‐Kee Low   +13 more
wiley   +1 more source

Combined Bouveret and Type IV Mirizzi Syndromes Treated by One-Stage Biliary and Gastrointestinal Reconstruction: A Case Report. [PDF]

Case Rep Surg
Ryu M, Chang CK, Le ST.
europepmc   +1 more source

Human Gallbladder Cancer Organoids

Cell Proliferation, EarlyView.
This guideline provides standardized requirements and quality control measures for human gallbladder cancer organoids, supporting their reliable application in research and precision medicine. It aims to promote methodological consistency, facilitate international collaboration, and accelerate translational research and clinical implementation.
Dongxi Xiang, Ting Gong, Yinjie Zhu, Bin Jia, Chen Zhang, Ning Tang, Weiping Wang, Yalong Wang, Laiping Zhong, Yanmei Zou, Jian Zhang, Zunqiang Zhou, Ligang Xing, Changchun Zhou, Dongyuan Zhu, Zengjun Liu, Gang Chen, Xiaoguang Wang, Zhan Wang, Aina He, Yonggang Wang, Zebing Liu, Jiabei Wang, Feng Xu, Ganglong Gao, Xiaonan Kang, Shuai Gong, Xianming Kong, Chunyan Dong, Aijin Ma, Gengming Niu, Guiying Wei, Hongling Zhao, Xiongxiong Lu, Jie Cao, Tongbiao Zhao, Zizhen Zhang, Yingbin Liu   +37 more
wiley   +1 more source

Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation

Cell Proliferation, EarlyView.
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Sai‐Sai Zhang, Haiyan Wang, Yi‐Sen Yang, Yi‐Hong Li, Defu Yu, Yushi Yao, Ruhong Zhou, Liquan Huang   +7 more
wiley   +1 more source

A case of spontaneous acalculous gallbladder perforation difficult to diagnose on computed tomography. [PDF]

J Surg Case Rep
Sato M, Hayashi K, Kobayashi A, Kubo K, Yamazaki N, Kobayashi R, Suzuki F, Asai D, Sannomiya Y, Tomita N, Yamada N, Watanabe T, Kakimoto M, Hasegawa K, Ogata K.   +14 more
europepmc   +1 more source