Results 21 to 30 of about 5,966 (169)

Successful preservation of functional right kidney with giant stones: A rare Chinese case report with literature review

Urology Case Reports
Renal calculi weighing over 200 g are relative rare in modern urological practice since most stones might cause renal dysfunction before reaching such size. We here reported an extremely rare case of giant stones in single kidney of a 72-year-old Chinese
Quanlei Wang, Xiyin Ye, Xiaohui Feng, Ting Lin, JingJing Liu, Yongdong Zhu, Yuanzan Zhu, Eddie Cheung, Jingxing Dai, Wanhong Liang, Yuan Liang, Sangui Wang   +11 more
doaj   +1 more source

Effect of liposome binding antisense oligonucleotide BP1003 on albumin-bound paclitaxel sensitivity in pancreatic cancer cells by inhibiting STAT3 [PDF]

Zhongguo aizheng zazhi
Background and purpose: The resistance of pancreatic cancer to albumin-bound paclitaxel affects the therapeutic effect and prognosis. Signal transducer and activator of transcription 3 (STAT3) is one of the important molecules regulating the chemotherapy
FU Hua, ZHOU Guochao, CAI Rongmin, SONG Xin, YANG Dinghua
doaj   +1 more source

Arsenic causing gallbladder cancer disease in Bihar

Scientific Reports, 2023
In recent times Gallbladder cancer (GBC) incidences increased many folds in India and are being reported from arsenic hotspots identified in Bihar. The study aims to establish association between arsenic exposure and gallbladder carcinogenesis.
Arun Kumar, Mohammad Ali, Vivek Raj, Arti Kumari, Mahesh Rachamalla, Som Niyogi, Dhruv Kumar, Ashok Sharma, Amit Saxena, Ghanish Panjawani, Preeti Jain, Ajay Vidyarthi, Navin Kumar, Mukesh Kumar, Pintoo Kumar Niraj, Md. Samiur Rahman, Akhouri Bishwapriya, Ranjit Kumar, Maiko Sakamoto, Santosh Kumar, Manisha Singh, Ashok Kumar Ghosh   +21 more
doaj   +1 more source

Identification of changes in bile composition in pancreaticobiliary reflux based on liquid chromatography/mass spectrometry metabolomics

BMC Gastroenterology
Introduction Pancreaticobiliary reflux (PBR) can induce gallstone formation; however, its pathogenic mechanism remains unclear. In this study, we explored the mechanism of PBR by the non-targeted metabolomic analysis of bile in patients with PBR ...
Xuanbo Da, Yukai Xiang, Hai Hu, Xiangyu Kong, Chen Qiu, Zhaoyan Jiang, Gang Zhao, Jingli Cai, Anhua Huang, Cheng Zhang, Chuanqi He, Beining Lv, Honglei Zhang, Yulong Yang   +13 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Risk factors and clinical characteristics of occult pancreaticobiliary reflux in benign gallbladder diseases

BMC Gastroenterology
Background This study aimed to elucidate the clinical characteristics of occult pancreaticobiliary reflux (OPBR) in benign gallbladder diseases, including gallbladder stone (GS), gallbladder polyp (GP), and gallbladder adenomyomatosis (GA).
Yukai Xiang, Chen Qiu, Hai Hu, Jingli Cai, Gang Zhao, Anhua Huang, Anan Xu, Chuanqi He, Cheng Zhang, Yulong Yang, Zhaoyan Jiang   +10 more
doaj   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Optimal indication for single-incision laparoscopic cholecystectomy in benign gallbladder diseases

Journal of Minimally Invasive Surgery, 2022
Laparoscopic cholecystectomy has become a basic procedure for cholecystectomy due to rapid recovery and cosmetic satisfaction after surgery, and it is currently the primary treatment for most benign gallbladder diseases.
Min-Su Park
doaj   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

Alteration of gut microbiota in association with cholesterol gallstone formation in mice

BMC Gastroenterology, 2017
Background The gut microbiome exerts extensive roles in metabolism of nutrients, pharmaceuticals, organic chemicals. Little has been known for the role of gut microbiota in regulating cholesterol and bile acids in association with gallstone formation ...
Qihan Wang, Long Jiao, Chuanqi He, Haidong Sun, Qu Cai, Tianquan Han, Hai Hu   +6 more
doaj   +1 more source