Results 41 to 50 of about 5,966 (169)

Research progress in precision medicine for type 2 diabetes based on the GLP-1

Frontiers in Endocrinology
Diabetes Mellitus (DM) represents a global health crisis, currently affecting approximately 9% of the world’s population. Its prevalence continues to rise steadily, with a noticeable trend toward onset at younger ages.
Sangui Wang, Sangui Wang, Chenrong Yuan, Haifeng Wang, Xiyin Ye, Shun Ruan, Li Yi, Wanyong Yang, Zhi Wang, Ni Wang, Jiahao Li, Xiaohui Feng, Yun Li, Yu Tian, Quanlei Wang, Quanlei Wang   +15 more
doaj   +1 more source

Differential Prognostic Impact of Prior Cholecystectomy Between Proximal and Distal Colorectal Cancer: A 12‐Year Retrospective Cohort Study of 3487 Consecutive Patients

Annals of Gastroenterological Surgery, EarlyView.
In this retrospective cohort of 3487 patients with CRC, history of CCY was associated with significantly worse prognosis in patients with proximal CRC but not in those with distal CRC. This differential prognostic impact showed a statistically significant interaction between tumor location and history of CCY and remained robust after PSM.
Masashi Tsunematsu, Koichiro Haruki, Kazuhiro Yanamoto, Takuo Takehana, Shunta Ishizaki, Mitsuru Yanagaki, Yoshihiro Shirai, Kenei Furukawa, Shinji Onda, Toru Ikegami   +9 more
wiley   +1 more source

Reappraisal of Real‐World Management of Acute Cholecystitis in Elderly Patients Based on the Adherence to Tokyo Guidelines 2018 (TG18): A Multicenter Study on Anzu HPB Surgical Meeting

Annals of Gastroenterological Surgery, EarlyView.
This multicenter retrospective study analyzes real‐world management of acute cholecystitis in patients aged ≥ 70 years across five institutions, focusing on adherence and intentional deviation from TG18 recommendations. By classifying treatment strategies as TG18‐accordant, more aggressive, or more conservative, we reappraise current practice patterns.
Yuta Kobayashi, Shojiro Hata, Ryo Oikawa, Tetsuya Nakazato, Hiroki Sakata, Hirokazu Yamaguchi, Yutaka Suzuki, Yoshihiro Sakamoto   +7 more
wiley   +1 more source

Analysis of risk factors for acute pancreatitis complicated with pancreatic sinistral portal hypertension and construction of predictive model

Frontiers in Physiology
Objective: Pancreatic sinistral portal hypertension (PSPH) is a common complication of acute pancreatitis (AP) and can cause massive gastrointestinal bleeding, which is one of the causes of AP-related mortality.
Xin Zhao, Xin Zhao, Tian-Yang Mao, Tian-Yang Mao, Kang-Yi Jiang, Kang-Yi Jiang, Qing-Yun Xie, Qing-Yun Xie, Jie Yang, Jie Yang, Bo Du, Bo Du, Zhi-Xu Wang, Zhi-Xu Wang, Jin-Qiang Fu, Jin-Qiang Fu, Feng-Wei Gao, Ze-Hua Lei, Ze-Hua Lei   +18 more
doaj   +1 more source

MicroRNA-125b predicts clinical outcome and suppressed tumor proliferation and migration in human gallbladder cancer

Tumor Biology, 2017
We intended to investigate the functional role and clinical relevance of microRNA-125b in human gallbladder cancer. Quantitative real-time polymerase chain reaction was used to examine microRNA-125b expression in gallbladder cancer cell lines, and 79 ...
Liang Yang, Sheng Huang, Hongbin Ma, Xiaoxiong Wu, Feiling Feng   +4 more
doaj   +1 more source

Survival Outcomes of Gemcitabine–Cisplatin–S‐1 Versus Gemcitabine–Cisplatin in Unresectable Biliary Tract Cancer: A Multicenter Retrospective Study With a Focus on Conversion Surgery

Annals of Gastroenterological Surgery, EarlyView.
In this multicenter retrospective study conducted by the Biliary Tract Club, we compared survival outcomes between gemcitabine–cisplatin–S‐1 (GCS) and gemcitabine–cisplatin (GC) in patients with unresectable biliary tract cancer, with a particular focus on conversion surgery. GCS was associated with longer overall and progression‐free survival compared
Hisashi Kosaka, Masahiko Kinoshita, Satoshi Yasuda, Satoru Kakizaki, Rie Sugimoto, Jun Sakata, Kiyonori Yamai, Takeshi Hatanaka, Yusuke Yamamoto, Toshifumi Sato, Toru Ishikawa, Takanori Morikawa, Jun Hanaoka, Haruki Mori, Hidenori Toyoda, Tsuyoshi Sanuki, Misaki Yokoi, Hiroyuki Shibata, Koji Fukuda, Kazuhito Kawata, Koji Amaya, Takashi Ito, Masaaki Hidaka, Atsushi Naganuma, Keishi Sugimachi, Satoshi Toshiyama, Makoto Yamasaki, Masaki Kaibori   +27 more
wiley   +1 more source

Anatomical simulation analysis of pancreaticobiliary junction in occult pancreaticobiliary reflux: based on Fluent study [PDF]

Waike lilun yu shijian
Objective Computational fluid dynamics software combined with finite element method was used to conduct 2D numerical simulation of pancreaticobiliary junction, and analyze the influence of biliopancreatic ampullary diaphragm, opening direction and shape ...
LÜ Beining, HOU Nianzong, XIANG Yukai, DA Xuanbo, YANG Yulong, TIAN Fuzhou
doaj   +1 more source

Emergency Cholecystectomy in Patients Classified as High Risk According to the Tokyo Guidelines 2018: A Real‐World Analysis

Annals of Gastroenterological Surgery, EarlyView.
Emergency cholecystectomy was evaluated in patients with acute cholecystitis classified as non‐recommended for surgery by the Tokyo Guidelines 2018. Major postoperative complications, rather than mortality, better reflected operative risk. Physiological instability, particularly ASA‐PS ≥ 3 and shock status, identified high‐risk patients, suggesting ...
Satoshi Mii, So Yamaki, Daisuke Hashimoto, Kazuki Matsumura, Hiroyuki Ishida, Hidetaka Miyazaki, Yuki Matsui, Yuji Ikeda, Tsukasa Ikeura, Sohei Satoi   +9 more
wiley   +1 more source

Impact of Recanalization on Liver Hypertrophy after Portal Vein Embolization and the Role of Re‐Embolization

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study of 249 patients undergoing hepatectomy after right portal vein embolization (PVE) demonstrated that major recanalization–defined as recanalization more than one segment within the embolized liver–was associated with impaired regeneration of the future liver remnant (FLR).
Masao Uemura, Shimpei Otsuka, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Rui Sato, Takeshi Aramaki, Akifumi Notsu, Katsuhiko Uesaka, Teiichi Sugiura   +9 more
wiley   +1 more source

Short‐Term Outcomes and Cost Drivers of Emergency Surgery for Acute Abdominal Disease in Super‐Elderly Patients: A Study in the Japanese Tertiary Care Hospital

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study analyzed patients aged ≥ 85 years undergoing emergency abdominal surgery, focusing on short‐term outcomes and inpatient cost structure under the Japanese DPC system. Although major complications occurred in 19.4% of patients, more than 70% were discharged home.
Yuta Kobayashi, Ryo Oikawa, Yumi Shibuya, Masakazu Tatsuno, Atsuya Kamiyama, Tsuyoshi Ozawa, Keiichiro Hara, Shojiro Hata, Hirokazu Yamaguchi   +8 more
wiley   +1 more source