Results 41 to 50 of about 125,645 (313)

Effect of liposome binding antisense oligonucleotide BP1003 on albumin-bound paclitaxel sensitivity in pancreatic cancer cells by inhibiting STAT3 [PDF]

Zhongguo aizheng zazhi
Background and purpose: The resistance of pancreatic cancer to albumin-bound paclitaxel affects the therapeutic effect and prognosis. Signal transducer and activator of transcription 3 (STAT3) is one of the important molecules regulating the chemotherapy
FU Hua, ZHOU Guochao, CAI Rongmin, SONG Xin, YANG Dinghua
doaj   +1 more source

Clinical Features and Outcomes of Gallbladder Polyps in Children

, 2022
BACKGROUND: Gallbladder polyps are rare lesions protruding into the gallbladder lumen with variable clinical presentation. No standard treatment algorithm has been developed for pediatric gallbladders, and the malignant potential of the gallbladder is ...
Berna Oğuz, SOYER, TUTKU, Mithat Haliloglu, TANYEL, FERİDUN CAHİT, Ferzeliyev1, Orxan, Soyer1, Tutku, OĞUZ, BERNA, Feridun Cahit Tanyel, BOYBEYİ TÜRER, ÖZLEM, Ferzeliyev, Orxan, Oğuz2, Berna, Tanyel1, Feridun Cahit, HALİLOĞLU, MİTHAT, Tutku Soyer, Özlem Boybey Türer, Haliloglu2, Mithat, Orxan Ferzeliyev, Türer1, Özlem Boybey   +17 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Risk factors and clinical characteristics of occult pancreaticobiliary reflux in benign gallbladder diseases

BMC Gastroenterology
Background This study aimed to elucidate the clinical characteristics of occult pancreaticobiliary reflux (OPBR) in benign gallbladder diseases, including gallbladder stone (GS), gallbladder polyp (GP), and gallbladder adenomyomatosis (GA).
Yukai Xiang, Chen Qiu, Hai Hu, Jingli Cai, Gang Zhao, Anhua Huang, Anan Xu, Chuanqi He, Cheng Zhang, Yulong Yang, Zhaoyan Jiang   +10 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Gallbladder volvulus

, 2022
Gallbladder volvulus is a rare entity. The condition results in rotation of the gallbladder on its mesentery along the axis of cystic duct and artery. Gallbladder volvulus is a condition in which the organ twists on its long axis to the point where its ...
Razana Mohd Omar, Salman Mirza, Omar, Razana Mohd, Turkmen, Suha, Zeinab AbdelMohsen Abdelrahman, Süha Türkmen, Abdelrahman, Zeinab AbdelMohsen, Mirza, Salman   +7 more
core   +1 more source

Rheumatoid Arthritis, Frailty, and Outcomes of Surgical Hospitalizations: A National Population‐Based Analysis

Arthritis Care &Research, EarlyView.
Objective Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective noncardiac surgery. Methods We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including adults
Ali Yazdanyar, Joshua Baker, Katherine D. Wysham, Mohammed Yousufuddin, Farah Acher Kaiksow, Michael M. Ward   +5 more
wiley   +1 more source

Optimal indication for single-incision laparoscopic cholecystectomy in benign gallbladder diseases

Journal of Minimally Invasive Surgery, 2022
Laparoscopic cholecystectomy has become a basic procedure for cholecystectomy due to rapid recovery and cosmetic satisfaction after surgery, and it is currently the primary treatment for most benign gallbladder diseases.
Min-Su Park
doaj   +1 more source

Torsion of the Gallbladder [PDF]

Journal of Gastrointestinal Surgery, 2012
A 77-year-old woman was seen with progressive abdominal pain.A CT scan was made and showed a large gallbladder extending into the right lower abdomen. Ultrasound was performed but demonstrated no gallstones. Laparoscopy showed a tordated, necrotic gallbladder that was attached to the liver only by the cystic artery and cystic duct.
Boonstra, Elizabeth A., van Etten, Boudewijn, Prins, Ted R., Sieders, Egbert, van Leeuwen, Barbara L.   +4 more
openaire   +2 more sources

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

Advanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong, Chi Cong Nguyen, Hannah Thuy Truong, Kefan Zhu, Adrienne Ji, James Davies, Emanuele Nicotra, Bibhu Sharma, Jingjing Wan, Patrick Pruscino, Shing Wai Wong, Hoang‐Phuong Phan, Phuoc Thien Phan, Nigel H. Lovell, Thanh Nho Do   +14 more
wiley   +1 more source