Results 61 to 70 of about 125,645 (313)

En bloc total biliary resection hepatectomy for the treatment of gallbladder adenosquamous carcinoma: a case report

, 2022
Introduction: Gallbladder cancer is a rare type of biliary tract malignancy with poorly defined pathogenesis, difficult treatment and often inoperable. Case Report: A 84-year-old male presented with pain in the right
Rafael Mello Fontolan Vieira, Geraldo Correa Tenório Siqueira, Gabriel Domingues da Costa-Neto, Julia Soriano Vaz Durante, Leandra Ernst Kerche   +4 more
core   +1 more source

Comparative Evaluation of Chelator‐Conjugated Peptides for Lead‐Labeled SSTR2‐Targeted Theranostics: Integrated Computational Modeling and Preclinical Validation

Advanced Science, EarlyView.
The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim, Na Yeon Han, Ayman Muzammal, Jae Hun Ahn, Changkeun Im, Sujin Kim, Sairan Eom, Choong Mo Kang, Ku Kang, Yong Jin Lee, Kyo Chul Lee, Michael K. Schultz, Dongyoul Lee   +12 more
wiley   +1 more source

Biliary Sepsis Due to Recurrent Acute Calculus Cholecystitis (ACC) in a High Surgical-Risk Elderly Patient: An Unexpected Complication

Pathogens, 2022
Acute calculus cholecystitis (ACC) is increasing in frequency within an ageing population, in which biliary tract infection, including cholecystitis and cholangitis, is the second most common cause of sepsis, with higher morbidity and mortality rates ...
Giacomo Sermonesi, Alessia Rampini, Girolamo Convertini, Raffaele Bova, Nicola Zanini, Riccardo Bertelli, Carlo Vallicelli, Francesco Favi, Giacomo Stacchini, Enrico Faccani, Nicola Fabbri, Fausto Catena   +11 more
doaj   +1 more source

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

Mediating role of emotional intelligence in the relationship between dual work stress and reflective ability among junior nurses

BMC Nursing
Background Junior nurses constitute the backbone of the nursing workforce, and their reflective ability is essential for clinical decision-making, as well as for driving innovation and improvement in nursing practices. Although numerous studies emphasize
Mingfang Zhang, Junxian Wu, Yanting Yang, Jingru Song, Qin Shen   +4 more
doaj   +1 more source

Research progress in precision medicine for type 2 diabetes based on the GLP-1

Frontiers in Endocrinology
Diabetes Mellitus (DM) represents a global health crisis, currently affecting approximately 9% of the world’s population. Its prevalence continues to rise steadily, with a noticeable trend toward onset at younger ages.
Sangui Wang, Sangui Wang, Chenrong Yuan, Haifeng Wang, Xiyin Ye, Shun Ruan, Li Yi, Wanyong Yang, Zhi Wang, Ni Wang, Jiahao Li, Xiaohui Feng, Yun Li, Yu Tian, Quanlei Wang, Quanlei Wang   +15 more
doaj   +1 more source

TTC21B: From Modifier to Causative Gene in Joubert Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic pathogenic variants in TTC21B, encoding the retrograde intraflagellar transport protein IFT139, are a known cause of renal and skeletal ciliopathies. Single heterozygous variants in this gene were found to be enriched in a cohort of patients with various ciliopathy phenotypes, including three individuals with Joubert syndrome (JS), a
Valentina Serpieri, Fulvio D'Abrusco, Anna Pichiecchio, Thouraya Ben Younes, Ichraf Kraoua, Enza Maria Valente   +5 more
wiley   +1 more source

Hepatic morphology and serum biochemical profile according to dry and rainy seasons in Pygocentrus nattereri (Characiformes: Serrasalmidae)

The Anatomical Record, EarlyView.
Abstract This study investigated the physiological and morphological adaptations of the liver of the carnivorous fish Pygocentrus nattereri (piranha) in response to seasonal variations (dry and rainy seasons) in the Brazilian Pantanal. The objective was to describe how the liver, a central organ in metabolic regulation, responds to environmental ...
Maria Eduarda Corona Garcia, Sandriely F. Marcondes, Mayara S. Siqueira, Taynara R. F. Leão, Robson A. Rodrigues, Karine N. N. Farias, André L. N. Silva, Karin Virgínia Kuibida, Lilian Franco‐Belussi, Carlos E. Fernandes   +9 more
wiley   +1 more source

Analysis of risk factors for acute pancreatitis complicated with pancreatic sinistral portal hypertension and construction of predictive model

Frontiers in Physiology
Objective: Pancreatic sinistral portal hypertension (PSPH) is a common complication of acute pancreatitis (AP) and can cause massive gastrointestinal bleeding, which is one of the causes of AP-related mortality.
Xin Zhao, Xin Zhao, Tian-Yang Mao, Tian-Yang Mao, Kang-Yi Jiang, Kang-Yi Jiang, Qing-Yun Xie, Qing-Yun Xie, Jie Yang, Jie Yang, Bo Du, Bo Du, Zhi-Xu Wang, Zhi-Xu Wang, Jin-Qiang Fu, Jin-Qiang Fu, Feng-Wei Gao, Ze-Hua Lei, Ze-Hua Lei   +18 more
doaj   +1 more source

Rib-lifting method for retraction of the low-lying costal arch in laparoscopic cholecystectomy of gallbladder torsion with kyphoscoliosis [PDF]

, 2009
Gallbladder torsion is a rare entity. Recently, laparoscopic cholecystectomy has become accepted as a standard operation for gallbladder torsion. Unfortunately, kyphoscoliosis is a risk factor of gallbladder torsion, and kyphoscoliosis results in a low ...
Adachi, Tomohiko, Tsuneoka, Noritsugu, Tajima, Yoshitsugu, Kuroki, Tamotsu, Kanematsu, Takashi   +4 more
core