Results 51 to 60 of about 160,829 (310)
BMC GastroenterologyBackground This study aimed to elucidate the clinical characteristics of occult pancreaticobiliary reflux (OPBR) in benign gallbladder diseases, including gallbladder stone (GS), gallbladder polyp (GP), and gallbladder adenomyomatosis (GA).
Yukai Xiang +10 more
doaj +1 more source
Frontiers in Endocrinology, 2023 Ectopic adrenocorticotropic hormone syndrome (EAS) is a condition of hypercortisolism caused by non-pituitary tumors that secrete adrenocorticotropic hormone (ACTH). A rare occurrence of this syndrome is due to an ACTH-producing neuroendocrine tumor that
Xiaofang Zhang +4 more
doaj +1 more source
Indomethacin decreases viscosity of gallbladder bile in patients with cholesterol gallstone disease [PDF]
, 1993 There is experimental evidence that inhibition of cyclooxygenase with nonsteroidal anti-inflammatory drugs may decrease cholesterol gall-stone formation and mitigate biliary pain in gall-stone patients.
Brandl, H. +8 more
core +1 more source
Annals of Oncology, 1999 Carcinoma of the gallbladder has an unusual geographic and demographic distribution being more common in Israel, Bolivia, Chile and in Southwestern native Americans in the United States. Chronic cholecystitis, choledochal cysts and significantly high body mass index are associated risk factors.
openaire +2 more sources
A 3D In Vitro Model of the Human Hepatobiliary Junction
Advanced Science, EarlyView.A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield +13 more
wiley +1 more source
Association of diverse bacterial communities in human bile samples with biliary tract disorders: a survey using culture and polymerase chain reaction-denaturing gradient gel electrophoresis methods [PDF]
, 2016 Bacterial infection is considered a predisposing factor for disorders of the biliary tract. This study aimed to determine the diversity of bacterial communities in bile samples and their involvement in the occurrence of biliary tract diseases. A total of
Alebouyeh, M. +5 more
core +1 more source
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou +9 more
wiley +1 more source
Alteration of gut microbiota in association with cholesterol gallstone formation in mice
BMC Gastroenterology, 2017 Background The gut microbiome exerts extensive roles in metabolism of nutrients, pharmaceuticals, organic chemicals. Little has been known for the role of gut microbiota in regulating cholesterol and bile acids in association with gallstone formation ...
Qihan Wang +6 more
doaj +1 more source
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
Advanced Science, EarlyView.An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source